Overview

  • Product name

    Anti-Clavesin 1 + 2 antibody
  • Description

    Rabbit polyclonal to Clavesin 1 + 2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human Clavesin 1 + 2 conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q8IUQ0

  • Positive control

    • Rat brain and mouse fetal liver tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab203664 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 41, 38 kDa.
IHC-P 1/100 - 1/500.

(or 1/50 - 1/200 using a fluorescent secondary antibody).

Target

  • Relevance

    Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009). Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008).
  • Cellular localization

    Golgi Apparatus, Cytoplasmic vesicle, Endosome, Membrane.
  • Database links

  • Alternative names

    • bA160A10.4 antibody
    • C6orf212 antibody
    • C6orf213 antibody
    • Clavesin 1 antibody
    • Clavesin 2 antibody
    • CRALBPL antibody
    • FLJ37248 antibody
    • MGC120572 antibody
    • MGC34646 antibody
    • OTTHUMP00000017122 antibody
    • Retinaldehyde binding protein 1 like 1 antibody
    • Retinaldehyde binding protein 1 like 2 antibody
    • RLBP1L1 antibody
    • RLBP1L2 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat brain tissue labeling Clavesin 1 + 2 with ab203664 at 1/100 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded mouse fetal liver tissue labeling Clavesin 1 + 2 with ab203664 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

References

ab203664 has not yet been referenced specifically in any publications.

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