Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.02% Sodium azide
Constituents: 60% PBS, 40% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab121524 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/10 - 1/20. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionMay be involved in mediating calcium-activated chloride conductance.
Tissue specificityPrimarily expressed in the digestive tract, mainly in colon. Detected in smaller amounts in brain, urogenital organs, testis, and salivary and mammary glands. Highly expressed in the epithelial layer and submucosal gland of the inferior turbinate mucosa. Lower levels in the epithelial layer of nasal polyp.
Sequence similaritiesBelongs to the CLCR family.
Contains 1 VWFA domain.
modificationsProcessed at a monobasic residue to yield a larger N-terminal and a smaller C-terminal cleavage products of 90 to 110 and 30 to 35 kDa, respectively.
Cellular localizationCell membrane. Apical cell membrane. Secreted. The C-terminus 30 kDa form is anchored to the membrane (By similarity). The N-terminus 110 kDa form is released from the membrane triggered by an unknown stimulus.
- Information by UniProt
- 30 kDa form antibody
- CaCC-2 antibody
- Calcium-activated chloride channel family member 4 antibody
ab121524 has not yet been referenced specifically in any publications.