Validated using a knockout cell line

Recombinant Anti-Cleaved PARP1 antibody [Y34] (ab32561)

Publishing research using ab32561? Please let us know so that we can cite the reference in this datasheet.

ab32561 has been referenced in 26 publications.

  • Chen Y  et al. Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCe-NF-?B signaling pathway and VEGF-C/ Bcl-2 expression. Mol Cancer 18:1 (2019). PubMed: 30609930
  • Ma C  et al. Emodin induces apoptosis and autophagy of fibroblasts obtained from patient with ankylosing spondylitis. Drug Des Devel Ther 13:601-609 (2019). PubMed: 30809091
  • Yang L  et al. Sodium selenite induces apoptosis and inhibits autophagy in human synovial sarcoma cell line SW982 in vitro. Mol Med Rep 17:6560-6568 (2018). PubMed: 29512717
  • Li JW  et al. Six2 is negatively correlated with good prognosis and decreases 5-FU sensitivity via suppressing E-cadherin expression in hepatocellular carcinoma cells. Biomed Pharmacother 104:204-210 (2018). WB ; Human . PubMed: 29772441
  • Li N  et al. Tanshinone IIA effects on ovarian cancer cell line. J Pharm Pharmacol 70:1369-1377 (2018). PubMed: 29943422
  • Khawar IA  et al. Three Dimensional Mixed-Cell Spheroids Mimic Stroma-Mediated Chemoresistance and Invasive Migration in hepatocellular carcinoma. Neoplasia 20:800-812 (2018). PubMed: 29981501
  • Zhang HW  et al. Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3K? mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells. Sci Rep 8:11255 (2018). PubMed: 30050147
  • Zhu J  et al. Beclin1 overexpression suppresses tumor cell proliferation and survival via an autophagy-dependent pathway in human synovial sarcoma cells. Oncol Rep 40:1927-1936 (2018). PubMed: 30066884
  • Shen P  et al. The protective effects of total paeony glycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway. Mol Med Rep 18:3332-3340 (2018). PubMed: 30066927
  • Jiao S  et al. Inhibition of CYFIP2 promotes gastric cancer cell proliferation and chemoresistance to 5-fluorouracil through activation of the Akt signaling pathway. Oncol Lett 13:2133-2140 (2017). WB ; Human . PubMed: 28454373
  • Liu C  et al. 16-Hydroxycleroda-3, 13-dien-15, 16-olide inhibits the proliferation and induces mitochondrial-dependent apoptosis through Akt, mTOR, and MEK-ERK pathways in human renal carcinoma cells. Phytomedicine 36:95-107 (2017). PubMed: 29157834
  • Song Z  et al. Blockade of sonic hedgehog signaling decreases viability and induces apoptosis in retinoblastoma cells: The key role of the PI3K/Akt pathway. Oncol Lett 14:4099-4105 (2017). PubMed: 28943916
  • Kuo JR  et al. Cisplatin-induced regulation of signal transduction pathways and transcription factors in p53-mutated subclone variants of hepatoma cells: Potential application for therapeutic targeting. Oncol Lett 12:3723-3730 (2016). PubMed: 27895723
  • Peh J  et al. The Combination of Vemurafenib and Procaspase-3 Activation Is Synergistic in Mutant BRAF Melanomas. Mol Cancer Ther 15:1859-69 (2016). PubMed: 27297867
  • Gao L  et al. Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats. Front Pharmacol 6:215 (2015). WB ; Rat . PubMed: 26483688
  • Zhou ZD  et al. F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy. Hum Mol Genet 24:6314-30 (2015). PubMed: 26310625
  • Guo W  et al. Targeting GRP75 improves HSP90 inhibitor efficacy by enhancing p53-mediated apoptosis in hepatocellular carcinoma. PLoS One 9:e85766 (2014). WB ; Human . PubMed: 24465691
  • Chihara T  et al. Caspase inhibition in select olfactory neurons restores innate attraction behavior in aged Drosophila. PLoS Genet 10:e1004437 (2014). IHC-FoFr . PubMed: 24967585
  • Cui SX  et al. 13F-1, a novel 5-fluorouracil prodrug containing an Asn-Gly-Arg (NO2) COOCH3 tripeptide, inhibits human colonic carcinoma growth by targeting Aminopeptidase N (APN/CD13). Eur J Pharmacol 734:50-9 (2014). PubMed: 24726845
  • Licciulli S  et al. Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53. Cancer Res 73:5974-84 (2013). PubMed: 23943799
  • Ghadimi MP  et al. Survivin is a viable target for the treatment of malignant peripheral nerve sheath tumors. Clin Cancer Res 18:2545-57 (2012). WB . PubMed: 22407831
  • Le TD  et al. Capsaicin-induced apoptosis of FaDu human pharyngeal squamous carcinoma cells. Yonsei Med J 53:834-41 (2012). WB . PubMed: 22665354
  • Wang L  et al. Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model. PLoS One 6:e24405 (2011). IHC-P ; Human . PubMed: 21931707
  • Cheong JK  et al. IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1d/? and Wnt/ß-catenin independent inhibition of mitotic spindle formation. Oncogene 30:2558-69 (2011). WB ; Human . PubMed: 21258417
  • Hornigold N  et al. Upregulation of Hic-5 in glomerulosclerosis and its regulation of mesangial cell apoptosis. Kidney Int 77:329-38 (2010). WB ; Human . PubMed: 20010548
  • Yoon MJ  et al. Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells. Free Radic Biol Med 48:713-26 (2010). PubMed: 20036734

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