Anti-CLEC2D antibody (ab111105)
Key features and details
- Goat polyclonal to CLEC2D
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CLEC2D antibody
See all CLEC2D primary antibodies -
Description
Goat polyclonal to CLEC2D -
Host species
Goat -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Cow, Dog -
Immunogen
Synthetic peptide, conjugated to KLH corresponding to internal sequence amino acids of Human CLEC2D.
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Positive control
- Human placenta and tonsil tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab111105 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. -
Tissue specificity
Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T and B lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. -
Sequence similarities
Contains 1 C-type lectin domain. -
Cellular localization
Endoplasmic reticulum and Cell membrane. Cell surface. - Information by UniProt
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Database links
- Entrez Gene: 29121 Human
- Omim: 605659 Human
- SwissProt: Q9UHP7 Human
- Unigene: 268326 Human
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Alternative names
- C type lectin related f antibody
- C type lectin superfamily 2, member D antibody
- C-type lectin domain family 2 member D antibody
see all
Images
Datasheets and documents
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Datasheet download
References (0)
ab111105 has not yet been referenced specifically in any publications.