Key features and details
- Rabbit polyclonal to CLIC6
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-CLIC6 antibody
DescriptionRabbit polyclonal to CLIC6
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
- Human pancreas tissue.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab204566 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionMay insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport.
Tissue specificityExpressed in brain, placenta, pancreas and liver.
Sequence similaritiesBelongs to the chloride channel CLIC family.
Contains 1 GST C-terminal domain.
DomainMembers of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
Cellular localizationCytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane.
- Information by UniProt
- Chloride channel form A antibody
- Chloride intracellular channel 6 antibody
- Chloride intracellular channel protein 6 antibody
ab204566 has not yet been referenced specifically in any publications.