Overview

  • Product name

    Clindamycin hydrochloride, Lincosamide antibiotic
  • Description

    Lincosamide antibiotic
  • Biological description

    Lincosamide antibiotic. Binds to the 23s portion of the 50S subunit of the bacterial ribosome inhibiting ribosomal translocation and protein synthesis. Orally active.
  • Purity

    > 87%
  • CAS Number

    21462-39-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2S,4R)-N-[(1S,2S)-2-Chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
  • Molecular weight

    461.44
  • Molecular formula

    C18H34Cl2N2O5S
  • PubChem identifier

    16051951
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)O)O)O)C(C)Cl.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Saridomichelakis MN  et al. Serum pharmacokinetics of clindamycin hydrochloride in normal dogs when administered at two dosage regimens. Vet Dermatol 22:429-35 (2011). Read more (PubMed: 21418348) »
  • Johnston TP  et al. Canine periodontal disease control using a clindamycin hydrochloride gel. J Vet Dent 28:224-9 (2011). Read more (PubMed: 22416621) »
  • Batzias GC  et al. Clindamycin bioavailability and pharmacokinetics following oral administration of clindamycin hydrochloride capsules in dogs. Vet J 170:339-45 (2005). Read more (PubMed: 16266847) »

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