Overview

  • Product name

    Clioquinol, Metal chelator and ionophore
  • Description

    Metal chelator and ionophore
  • Biological description

    Metal chelator and ionophore with beneficial effects in animal models of neurodegenerative diseases (Alzheimer's, Parkinson's and Huntington's disease). Effects on Alzheimer's disease attributed to copper and zinc chelation or increased level of a metalloprotease. Other actions reported including iron chelation, inhibition of Huntington expression from its mRNA, proteasome inhibition when complexed with copper, and stimulation of tumor necrosis factor-α secretion. Also inhibitor of CLK-1/MCLK1 (an aging-associated protein).
  • Purity

    > 97%
  • CAS Number

    130-26-7
  • Chemical structure

    Chemical Structure

Properties

References

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