Anti-CLLD8/SETDB2 antibody - N-terminal (ab155243)

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Overview

  • Product name
    Anti-CLLD8/SETDB2 antibody - N-terminal
    See all CLLD8/SETDB2 primary antibodies
  • Description
    Rabbit polyclonal to CLLD8/SETDB2 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human CLLD8/SETDB2 aa 1-160 (N terminal).
    Database link: Q96T68

  • Positive control
    • WB: SK-N-SH whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab155243 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 82 kDa.

Target

  • Function
    Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.
  • Tissue specificity
    Ubiquitous. Highest expression in heart, testis and ovary.
  • Sequence similarities
    Belongs to the histone-lysine methyltransferase family.
    Contains 1 MBD (methyl-CpG-binding) domain.
    Contains 1 pre-SET domain.
    Contains 1 SET domain.
  • Cellular localization
    Nucleus. Chromosome.
  • Information by UniProt
  • Database links
    • Alternative names
      • C13orf4 antibody
      • Chromosome 13 open reading frame 4 antibody
      • Chronic lymphocytic leukemia deletion region 8 antibody
      • Chronic lymphocytic leukemia deletion region gene 8 antibody
      • Chronic lymphocytic leukemia deletion region gene 8 protein antibody
      • Clld8 antibody
      • CLLL8 antibody
      • Gm293 antibody
      • H3-K9-HMTase antibody
      • Histone H3-K9 methyltransferase antibody
      • Histone-lysine N-methyltransferase SETDB2 antibody
      • KMT1F antibody
      • Lysine N-methyltransferase 1F antibody
      • Probable histone-lysine N-methyltransferase H3 lysine-9 specific antibody
      • SEB2 antibody
      • SET domain bifurcated 2 antibody
      • SET domain protein, bifurcated, 2 antibody
      • SETB2_HUMAN antibody
      • Setdb2 antibody
      see all

    Images

    • Western blot - Anti-CLLD8/SETDB2 antibody - N-terminal (ab155243)
      Western blot - Anti-CLLD8/SETDB2 antibody - N-terminal (ab155243)
      Anti-CLLD8/SETDB2 antibody - N-terminal (ab155243) at 1/1000 dilution + SK-N-SH whole cell lysate at 30 µg

      Predicted band size: 82 kDa



      7.5% SDS PAGE

    References

    ab155243 has not yet been referenced specifically in any publications.

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