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Rabbit monoclonal [EPR12197(B)] to CLN5
ICC/IF more details Unsuitable for:
Flow Cyt or IP
Mouse, Rat, Human
Synthetic peptide within Human CLN5 aa 150-250 (Cysteine residue). The exact sequence is proprietary.
Database link: O75503 (Peptide available as ab204069)
Fetal kidney, T47-D and A431 lysates; Human kidney tissue; A431 cells.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
This product is a recombinant rabbit monoclonal antibody.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
1/100 - 1/250.
1/100 - 1/250.
Is unsuitable for Flow Cyt or IP.
Involvement in disease
Defects in CLN5 are the cause of neuronal ceroid lipofuscinosis type 5 (CLN5) [MIM:256731]; also known as Finnish variant late-infantile neuronal ceroid lipofuscinosis (vLINCL). A form of neuronal ceroid lipofuscinosis. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material, and clinically by seizures, dementia, visual loss, and/or cerebral atrophy. The lipopigment patterns observed most often in neuronal ceroid lipofuscinosis type 5 comprise mixed combinations of granular, curvilinear, and fingerprint profiles.
Belongs to the CLN5 family.
Information by UniProt
Ceroid lipofuscinosis neuronal 5 antibody
Ceroid-lipofuscinosis neuronal protein 5 antibody
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"