Key features and details
- Mouse monoclonal [2187C2a] to CLNS1A/CLCI
- Suitable for: Dot blot, WB
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-CLNS1A/CLCI antibody [2187C2a]
See all CLNS1A/CLCI primary antibodies
DescriptionMouse monoclonal [2187C2a] to CLNS1A/CLCI
Tested applicationsSuitable for: Dot blot, WBmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to CLNS1A/CLCI (C terminal).
This product was previously labelled as CLNS1A
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.0225% Potassium chloride, 0.0204% Monobasic dihydrogen potassium phosphate, 0.1136% Dibasic monohydrogen sodium phosphate, 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, 0.1312% Sodium phosphate
Concentration information loading...
PurityProtein G purified
Purification notesab53667 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Our Abpromise guarantee covers the use of ab53667 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Dot blot||Use at an assay dependent dilution.|
|WB||Use at an assay dependent dilution. Predicted molecular weight: 26 kDa.|
FunctionThe interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.
Sequence similaritiesBelongs to the pICln family.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationCytoplasm. Nucleus. Cytoplasm > cytoskeleton. A small fraction is also associated with the cytoskeleton.
- Information by UniProt
- Chloride channel antibody
- Chloride channel nucleotide sensitive 1A antibody
- Chloride channel regulatory protein antibody
Staining of immunized recombinant protein using anti-CLNS1A/CLCI antibody [2187C2a](ab53667).
Predicted band size: 26 kDa
Observed band size: 39 kDa why is the actual band size different from the predicted?
ab53667 has not yet been referenced specifically in any publications.