Product nameAnti-CLNS1A/CLCI antibody - C-terminal
See all CLNS1A/CLCI primary antibodies
DescriptionRabbit polyclonal to CLNS1A/CLCI - C-terminal
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human CLNS1A/CLCI (C terminal).
Database link: P54105
- HuvEc, K562, HeLa, HepG2, A549 and Jurkat cell extracts.
This product was previously labelled as CLNS1A
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS, 0.87% Sodium chloride
PBS without Mg2+ and Ca2+.
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab196744 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Our Abpromise guarantee covers the use of ab196744 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 26 kDa.|
FunctionThe interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.
Sequence similaritiesBelongs to the pICln family.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationCytoplasm. Nucleus. Cytoplasm > cytoskeleton. A small fraction is also associated with the cytoskeleton.
- Information by UniProt
- Chloride channel antibody
- Chloride channel nucleotide sensitive 1A antibody
- Chloride channel regulatory protein antibody
All lanes : Anti-CLNS1A/CLCI antibody - C-terminal (ab196744) at 1/500 dilution
Lane 1 : HepG2 cell extract
Lane 2 : Jurkat cell extract
Lane 3 : K562 cell extract
Lane 4 : A549 cell extract
Lane 5 : HuvEc cell extract
Lane 6 : HeLa cell extract
Lane 7 : HeLa cell extract with synthesized peptide
Predicted band size: 26 kDa
ab196744 has not yet been referenced specifically in any publications.