Closantel, antibacterial and antiparasitic agent (ab145774)

Overview

  • Product name

    Closantel, antibacterial and antiparasitic agent
  • Description

    Antibacterial and antiparasitic agent
  • Biological description

    Antibacterial and antiparasitic agent. Inhibits the KinA/Spo0F system (IC50 = 3.8 μM). Shows activity against Gram-positive bacteria and shows antiparasitic effects in vivo.
  • Purity

    > 99%
  • CAS Number

    57808-65-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ballent M  et al. Intestinal drug transport: ex vivo evaluation of the interactions between ABC transporters and anthelmintic molecules. J Vet Pharmacol Ther 37:332-7 (2014). Read more (PubMed: 24611483) »
  • Iezzi S  et al. Closantel plasma and milk disposition in dairy goats: assessment of drug residues in cheese and ricotta. J Vet Pharmacol Ther 37:589-94 (2014). Read more (PubMed: 24903569) »
  • Garner AL  et al. Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus. J Med Chem 54:3963-72 (2011). Read more (PubMed: 21534605) »

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