Clozapine, Atypical antipsychotic (ab120019)

Submit a review Q&A (1)References (2)

Overview

  • Product name
    Clozapine, Atypical antipsychotic
  • Description
    Atypical antipsychotic
  • Biological description
    Atypical antipsychotic compound. Broad range of actions including antagonism at D4, D2, 5-HT2A, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptors. Also agonist at muscarinic receptors.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Josselyn SA  et al. Behavioral effects of clozapine and dopamine receptor subtypes. Neurosci Biobehav Rev 21:531-58 (1997). Read more (PubMed: 9353791) »
  • Brunello N  et al. New insights into the biology of schizophrenia through the mechanism of action of clozapine. Neuropsychopharmacology 13:177-213 (1995). Read more (PubMed: 8602893) »
See all 2 Publications for this product

Publishing research using ab120019? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

Question

Customer kindly contacted us regarding ab120019 solubility limits after diluting in 2 eq. HCL to 50mM. He is injecting into rodents but needs a more dilute HCL concentration than 50mM, so he needs to dilute further in saline prior to injection. He is wondering how if the Clozapine will remain soluble with further dilution in saline.

Read More
Answer



Our chemists have checked the solubility of 50mM Clozapine in 2 eq. HCl and also further dilutions in saline. We can confirm that the solubility was maintained for further dilutions as follows:

50mM in 2 eq. HCl (Stock solution)

25mM 1:1 dilution in saline

10mM 1:4 dilution in saline

5mM 1:9 dilution in saline

Saline is 0.9% NaCl unbuffered in de-ionized water.

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up