Overview

  • Product name

    Anti-CMKLR1 antibody - N-terminal
    See all CMKLR1 primary antibodies
  • Description

    Rabbit polyclonal to CMKLR1 - N-terminal
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except FZD6 (11%).
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    An 18 amino acid synthetic peptide from the N-terminal extracellular domain of Human CMKLR1 (NP_004063.1).

  • Positive control

    • Human thymus tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab150491 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 7 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
  • Tissue specificity

    Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Developmental stage

    Expressed during bone development.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CHEMERINR antibody
    • Chemokine like receptor 1 antibody
    • Chemokine-like receptor 1 antibody
    • CHEMR23 antibody
    • CMKLR1 antibody
    • CML1_HUMAN antibody
    • DEZ antibody
    • G protein coupled receptor ChemR23 antibody
    • G protein coupled receptor DEZ antibody
    • G-protein coupled receptor ChemR23 antibody
    • G-protein coupled receptor DEZ antibody
    • Orphan G protein coupled receptor antibody
    • Orphan G protein coupled receptor Dez antibody
    • Resolvin E1 receptor antibody
    • RVER1 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human thymus tissue labelling CMKLR1 with ab150491 at 7 µg/ml

References

This product has been referenced in:

  • Jannaway M  et al. Resolvin E1, resolvin D1 and resolvin D2 inhibit constriction of rat thoracic aorta and human pulmonary artery induced by the thromboxane mimetic U46619. Br J Pharmacol 175:1100-1108 (2018). Read more (PubMed: 29352769) »
See 1 Publication for this product

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