Anti-CMKLR1 antibody - N-terminal (ab150491)
Key features and details
- Rabbit polyclonal to CMKLR1 - N-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CMKLR1 antibody - N-terminal
See all CMKLR1 primary antibodies -
Description
Rabbit polyclonal to CMKLR1 - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except FZD6 (11%). -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
An 18 amino acid synthetic peptide from the N-terminal extracellular domain of Human CMKLR1 (NP_004063.1).
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Positive control
- Human thymus tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150491 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 7 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| Notes |
|---|
|
IHC-P
Use a concentration of 7 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). -
Tissue specificity
Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Developmental stage
Expressed during bone development. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1240 Human
- Omim: 602351 Human
- SwissProt: Q99788 Human
- Unigene: 197143 Human
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Alternative names
- CHEMERINR antibody
- Chemokine like receptor 1 antibody
- Chemokine-like receptor 1 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CMKLR1 antibody - N-terminal (ab150491)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human thymus tissue labelling CMKLR1 with ab150491 at 7 µg/ml
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab150491 has been referenced in 1 publication.
- Jannaway M et al. Resolvin E1, resolvin D1 and resolvin D2 inhibit constriction of rat thoracic aorta and human pulmonary artery induced by the thromboxane mimetic U46619. Br J Pharmacol 175:1100-1108 (2018). PubMed: 29352769