Anti-CMPK2 antibody (ab139720)

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Overview

  • Product name

    Anti-CMPK2 antibody
    See all CMPK2 primary antibodies

  • Description

    Rabbit polyclonal to CMPK2

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Rat

  • Immunogen

    Synthetic peptide corresponding to 19 amino acid residues near the carboxy terminus of Human CMPK2 (NP_997198).

  • Positive control

    • Rat lung tissue lysate.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted.

  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Clonality

    Polyclonal

  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab139720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa.

Target

  • Function

    May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs.

  • Tissue specificity

    Among all investigated tumors, leukemia cells show the most abundant expression.

  • Sequence similarities

    Belongs to the thymidylate kinase family.

  • Cellular localization

    Mitochondrion.
  • Information by UniProt

  • Database links

    • Alternative names

      • 1200004E04Rik antibody
      • Cmpk2 antibody
      • CMPK2_HUMAN antibody
      • Cytidine monophosphate (UMP CMP) kinase 2, mitochondrial antibody
      • mitochondrial antibody
      • Mitochondrial UMP CMP kinase antibody
      • OTTHUMP00000200305 antibody
      • Thymidine monophosphate kinase 2 antibody
      • TMPK2 antibody
      • TYKi antibody
      • UMP CMP kinase 2, mitochondrial antibody
      • UMP CMP kinase 2, mitochondrial; cytidylate kinase 2 antibody
      • UMP CMPK2 antibody
      • UMP-CMP kinase 2 antibody
      see all

    Images

    • Western blot - Anti-CMPK2 antibody (ab139720)
      Western blot - Anti-CMPK2 antibody (ab139720)
      Anti-CMPK2 antibody (ab139720) at 1 µg/ml + Rat lung tissue lysate at 15 µg

      Predicted band size: 49 kDa

    References

    ab139720 has not yet been referenced specifically in any publications.

    Publishing research using ab139720? Please let us know so that we can cite the reference in this datasheet.

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