Anti-CMPK2 antibody (ab139720)
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Overview
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Product name
Anti-CMPK2 antibody
See all CMPK2 primary antibodies -
Description
Rabbit polyclonal to CMPK2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat -
Immunogen
Synthetic peptide corresponding to 19 amino acid residues near the carboxy terminus of Human CMPK2 (NP_997198).
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Positive control
- Rat lung tissue lysate.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle. Store undiluted. -
Storage buffer
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab139720 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. |
Target
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Function
May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor. Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion caused by long term treatment with ddC or other pyrimidine analogs. -
Tissue specificity
Among all investigated tumors, leukemia cells show the most abundant expression. -
Sequence similarities
Belongs to the thymidylate kinase family. -
Cellular localization
Mitochondrion. - Information by UniProt
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Database links
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Alternative names
- 1200004E04Rik antibody
- Cmpk2 antibody
- CMPK2_HUMAN antibody
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Images
Datasheets and documents
References
ab139720 has not yet been referenced specifically in any publications.