Product nameAnti-CMT2 antibody
See all CMT2 primary antibodies
DescriptionChicken polyclonal to CMT2
Tested applicationsSuitable for: WBmore details
Predicted to work with: Human
Synthetic peptide corresponding to CMT2 aa 1-126 (N terminal).
This product was previously labelled as MAD2L1 binding protein
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituent: PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab37584 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex.
Sequence similaritiesBelongs to the MAD2L1BP family.
Developmental stageDuring the cell cycle, levels increase and then remain constant until late mitosis after which they drop.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationNucleus. Cytoplasm > cytoskeleton > spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle.
- Information by UniProt
- Caught by MAD2 protein antibody
- CMT2 antibody
- dJ261G23.1 antibody
Anti-CMT2 antibody (ab37584) at 1/2000 dilution + E coli-derived fusion protein at 2.5 µg
Goat anti-IgY-HRP at 1/1000 dilution
Predicted band size: 31 kDa
Observed band size: 80 kDa why is the actual band size different from the predicted?
Predicted and actual molecular weights differ due to the use of a fusion protein.
ab37584 has not yet been referenced specifically in any publications.