Anti-CNGA4 antibody - N-terminal (ab170427)

Overview

  • Product name
    Anti-CNGA4 antibody - N-terminal
    See all CNGA4 primary antibodies
  • Description
    Rabbit polyclonal to CNGA4 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human CNGA4 aa 138-168 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: Q8IV77

  • Positive control
    • Mouse cerebellum tissue lysate; Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab170427 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 66 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance
    Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
  • Cellular localization
    Membrane; Multi-pass membrane protein.
  • Database links
  • Alternative names
    • Cgn2 antibody
    • CNCA2 antibody
    • CNG 4 antibody
    • CNG channel alpha 4 antibody
    • CNG4 antibody
    • CNG5 antibody
    • Cnga4 cyclic nucleotide gated channel alpha 4 antibody
    • CNGB2 antibody
    • Cyclic nucleotide gated cation channel alpha 4 antibody
    • Cyclic nucleotide gated channel alpha 4 antibody
    • Cyclic nucleotide gated channel beta 2 antibody
    • Cyclic nucleotide gated olfactory channel subunit OCNC2 antibody
    • MGC126168 antibody
    • MGC126169 antibody
    • MGC130316 antibody
    • OCNC2 antibody
    • OCNCb antibody
    • OCNCBETA antibody
    see all

Images

  • Anti-CNGA4 antibody - N-terminal (ab170427) at 1/100 dilution + Mouse cerebellum tissue lysate at 35 µg

    Predicted band size: 66 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue labeling CNGA4 with ab170427 at 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

References

ab170427 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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