Key features and details
- Rabbit polyclonal to CNNM4
- Suitable for: IP, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-CNNM4 antibody
See all CNNM4 primary antibodies
DescriptionRabbit polyclonal to CNNM4
Tested applicationsSuitable for: IP, WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Chimpanzee, Gorilla, Orangutan
- HeLa, 293T, Jurkat, mouse TCMK-1 and mouse NIH 3T3 whole cell lysates.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191207 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IP||Use at 2-10 µg/mg of lysate.|
|WB||1/1000 - 1/5000. Predicted molecular weight: 87 kDa.|
FunctionProbable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.
Tissue specificityWidely expressed. Highly expressed in heart.
Involvement in diseaseDefects in CNNM4 are the cause of Jalili syndrome (JALIS) [MIM:217080]. A syndrome characterized by the association of cone-rod dystrophy and amelogenesis imperfecta.
Sequence similaritiesBelongs to the ACDP family.
Contains 2 CBS domains.
Contains 1 DUF21 domain.
Cellular localizationCell membrane.
- Information by UniProt
- 430430O18Rik antibody
- ACDP4 antibody
- Ancient conserved domain protein 4 antibody
All lanes : Anti-CNNM4 antibody (ab191207) at 0.4 µg/ml
Lane 1 : HeLa whole cell lysate prepared using RIPA
Lane 2 : 293T whole cell lysate prepared using RIPA
Lane 3 : Jurkat whole cell lysate prepared using RIPA
Lane 4 : mouse TMCM-1 whole cell lysate prepared using NETN
Lane 5 : mouse NIH 3T3 whole cell lysate prepared using NETN
Lysates/proteins at 50 µg per lane.
Developed using the ECL technique.
Predicted band size: 87 kDa
Exposure time: 30 seconds
Immunoprecipitation analysis of HeLa whole cell lysate prepared using RIPA lysis buffer (1.0 mg per IP reaction; 20% of IP loaded) using ab191207 used at 6 µg per reaction lane 1. Lane 2 shows control IgG. For blotting ab191207 was used at 1 µg/ml. Chemiluminescence with an exposure time of 30 seconds.
ab191207 has not yet been referenced specifically in any publications.