Overview

  • Product name

    Anti-CNNM4 antibody - C-terminal
    See all CNNM4 primary antibodies
  • Description

    Rabbit polyclonal to CNNM4 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human CNNM4 (C terminal). The exact sequence is proprietary.
    Database link: Q6P4Q7

  • Positive control

    • IHC-P: Human ovarian carcinoma tissue. WB: U-87 MG whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab228831 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 87 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.
  • Tissue specificity

    Widely expressed. Highly expressed in heart.
  • Involvement in disease

    Defects in CNNM4 are the cause of Jalili syndrome (JALIS) [MIM:217080]. A syndrome characterized by the association of cone-rod dystrophy and amelogenesis imperfecta.
  • Sequence similarities

    Belongs to the ACDP family.
    Contains 2 CBS domains.
    Contains 1 DUF21 domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 430430O18Rik antibody
    • ACDP4 antibody
    • Ancient conserved domain protein 4 antibody
    • Ancient conserved domain-containing protein 4 antibody
    • cnnm4 antibody
    • CNNM4_HUMAN antibody
    • Cyclin and CBS domain divalent metal cation transport mediator 4 antibody
    • Cyclin M4 antibody
    • Cyclin-M4 antibody
    • FLJ42791 antibody
    • KIAA1592 antibody
    • Metal transporter CNNM4 antibody
    see all

Images

  • Paraffin-embedded human ovarian carcinoma tissue stained for ARFGAP3 using ab228831 at 1/250 dilution in immunohistochemical analysis.

  • Anti-CNNM4 antibody - C-terminal (ab228831) at 1/1000 dilution + U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell lysate at 30 µg

    Predicted band size: 87 kDa



    7.5% SDS-PAGE gel.

References

ab228831 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228831.
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