Overview

  • Product name

    Anti-CNTF antibody [AS23]
    See all CNTF primary antibodies
  • Description

    Mouse monoclonal [AS23] to CNTF
  • Host species

    Mouse
  • Tested applications

    Suitable for: ELISA, WB, IPmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant human CNTF

Properties

Applications

Our Abpromise guarantee covers the use of ab17284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IP
  • Application notes

    ELISA: This antibody has been used as a coating antibody at 10 ug/ml in a two site ELISA with PS2-B. Typically the ELISA has a working range of 0-20000 pg/ml and a sensitivity of 10 pg/ml when used with biotin conjugated CNTF antibody. Recommended sample volumes are 25-200 µl. Recovery of hCNTF in human plasma is typically > 85 in the ELISA.
    IP: This antibody has been used to immunoprecipitate >90% hCNTF in solution using a double-antibody method.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 24 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
    • Tissue specificity

      Nervous system.
    • Sequence similarities

      Belongs to the CNTF family.
    • Cellular localization

      Cytoplasm.
    • Information by UniProt
    • Database links

    • Alternative names

      • Ciliary neurotrophic factor antibody
      • CNTF antibody
      • CNTF_HUMAN antibody
      • HCNTF antibody

    References

    This product has been referenced in:

    • Millán-Rivero JE  et al. Human Wharton's jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors. Sci Rep 8:16299 (2018). Read more (PubMed: 30389962) »
    See 1 Publication for this product

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