Key features and details
- ApoE peptide mimetic.
- CAS Number: 514200-66-9
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameCOG 133, apolipoprotein peptide fragment
DescriptionApoE peptide mimetic.
ApoE peptide mimetic. Corresponds to amino acids 133-149 of human ApoE. Non-cometitive alpha-7 nicotinic acetylcholine receptor antagonist (IC50 = 445 nM). Inhibits NMDA receptor channel function via interaction with the low-density lipoprotein receptor-related protein. Reduces inflammation, demyleination and cellular infiltration in animal models of multiple sclerosis. Reduces markers of inflammation in 5-fluorouracil model of intestinal mucositis.
Storage instructionsShipped at room temperature. Store at -20°C.
Solubility overviewSoluble in DMSO to 100 mM
Refer to SDS for further information.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab269699 has not yet been referenced specifically in any publications.