COG 133, apolipoprotein peptide fragment (ab269699)

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Chemical Structure - COG 133, apolipoprotein peptide fragment (ab269699)

    Key features and details

    • ApoE peptide mimetic.
    • CAS Number: 514200-66-9
    • Soluble in DMSO to 100 mM
    • Form / State: Solid
    • Source: Synthetic

    Overview

    • Product name

      COG 133, apolipoprotein peptide fragment

    • Description

      ApoE peptide mimetic.

    • Biological description

      ApoE peptide mimetic. Corresponds to amino acids 133-149 of human ApoE. Non-cometitive alpha-7 nicotinic acetylcholine receptor antagonist (IC50 = 445 nM). Inhibits NMDA receptor channel function via interaction with the low-density lipoprotein receptor-related protein. Reduces inflammation, demyleination and cellular infiltration in animal models of multiple sclerosis. Reduces markers of inflammation in 5-fluorouracil model of intestinal mucositis. 

    • CAS Number

      514200-66-9

    • Chemical structure

      Chemical Structure

    Properties

    • Molecular weight

      2169.73

    • Molecular formula

      C97H181N37O19

    • Sequence

      LRVRLASHLRKLRKRLL

    • Storage instructions

      Shipped at room temperature. Store at -20°C.

    • Solubility overview

      Soluble in DMSO to 100 mM

    • Handling

      Refer to SDS for further information.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • Source

      Synthetic

    Images

    • Chemical Structure - COG 133, apolipoprotein peptide fragment (ab269699)
      Chemical Structure - COG 133, apolipoprotein peptide fragment (ab269699)

      Chemical structure of COG 133, apolipoprotein peptide fragment, 514200-66-9

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

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    ab269699 has not yet been referenced specifically in any publications.

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