Overview

  • Product name

  • Description

    Rabbit polyclonal to COG8/DOR1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rat, Cow
  • Immunogen

    Recombinant fragment within Human COG8/DOR1 (internal sequence). The exact sequence is proprietary.
    Database link: Q96MW5

  • Positive control

    • WB: Raji whole cell lysate. ICC/IF: A431 cells.
  • General notes

     This product was previously labelled as COG8

     

Properties

Applications

Our Abpromise guarantee covers the use of ab228583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 68 kDa.
ICC/IF 1/100 - 1/1000.

Target

  • Relevance

    COG8 is a component of the conserved oligomeric Golgi (COG) complex. This is a multiprotein complex that plays a structural role in the Golgi apparatus and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins and whose symptoms include severe psychomotor retardation, failure to thrive, seizures and dairy and wheat product intolerance. It is required for normal Golgi function.
  • Cellular localization

    Golgi apparatus; Peripheral membrane protein.
  • Database links

  • Alternative names

    • COG complex subunit 8 antibody
    • Component of oligomeric golgi complex 8 antibody
    • Conserved oligomeric Golgi complex component 8 dependent on RIC1 antibody
    • DOR1 antibody

Images

  • Anti-COG8/DOR1 antibody (ab228583) at 1/1000 dilution + Raji (human Burkitt's lymphoma cell line) whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 68 kDa



    7.5% SDS-PAGE

  • Methanol-fixed A431 (human epidermoid carcinoma cell line) cells stained for COG8/DOR1 (green) using ab228583 at 1/500 dilution in ICC/IF.

    Blue: Hoechst 33342 staining.

References

ab228583 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228583.
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