Overview

  • Product name

    Anti-COL6A5 antibody - C-terminal
  • Description

    Rabbit polyclonal to COL6A5 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cow, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 2427-2476 of Human COL6A5 (NP_694996).

  • Positive control

    • Fetal Heart lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab139651 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 290 kDa.

Target

  • Function

    Collagen VI acts as a cell-binding protein.
  • Tissue specificity

    Expressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular layers (at protein level).
  • Involvement in disease

    Note=Patients affected by atopic dermatitis display an abnormal distribution of COL29A1 mRNA and protein in skin suggesting that COL29A1 may be involved in the pathogenesis of the disease.
  • Sequence similarities

    Belongs to the type VI collagen family.
    Contains 10 VWFA domains.
  • Post-translational
    modifications

    Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix. Deposed in the extracellular matrix of skeletal muscle.
  • Information by UniProt
  • Database links

  • Alternative names

    • CO6A5_HUMAN antibody
    • COL29A1 antibody
    • Col6a5 antibody
    • Collagen alpha-1(XXIX) chain antibody
    • Collagen alpha-5(VI) chain antibody
    • Collagen antibody
    • Collagen, type VI, alpha 5 antibody
    • Collagen, type XXIX, alpha-1 antibody
    • EG665033 antibody
    • FLJ35880 antibody
    • Gm7455 antibody
    • von Willebrand factor A domain-containing protein 4 antibody
    • VWA4 antibody
    see all

Images

  • Anti-COL6A5 antibody - C-terminal (ab139651) at 1 µg/ml + Human Fetal Heart Lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Developed using the ECL technique.

    Predicted band size: 290 kDa


    Exposure time: 1 minute

References

ab139651 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab139651.
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