Overview

  • Product name

    Anti-COLEC11 antibody
  • Description

    Rabbit polyclonal to COLEC11
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human COLEC11 aa 26-271.
    Database link: Q9BWP8

  • Positive control

    • IHC-P: Human kidney tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab238585 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration.
  • Tissue specificity

    Ubiquitous.
  • Involvement in disease

    Defects in COLEC11 are the cause of 3MC syndrome type 2 (3MC2) [MIM:265050]. 3MC2 is an a disorder characterized by facial dysmorphism that includes hypertelorism, blepharophimosis, blepharoptosis and highly archedDE eyebrows, cleft lip and/or palate, craniosynostosis, learning disability and genital, limb and vesicorenal anomalies. The term 3MC syndrome includes Carnevale, Mingarelli, Malpuech, and Michels syndromes.
  • Sequence similarities

    Belongs to the COLEC10/COLEC11 family.
    Contains 1 C-type lectin domain.
    Contains 1 collagen-like domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • CL K1 antibody
    • CL K1 I antibody
    • CL K1 II antibody
    • CL K1 IIa antibody
    • CL K1 IIb antibody
    • CL-K1 antibody
    • CLK1 antibody
    • COL11_HUMAN antibody
    • COLEC 11 antibody
    • COLEC11 antibody
    • Collectin 11 antibody
    • Collectin kidney I antibody
    • Collectin kidney protein 1 antibody
    • Collectin sub family member 11 antibody
    • Collectin-11 antibody
    • Collectin11 antibody
    • DKFZp686N1868 antibody
    • MGC129470 antibody
    • MGC129471 antibody
    • MGC3279 antibody
    see all

Images

  • Paraffin-embedded human kidney tissue stained for COLEC11 with ab238585 at a 1/100 dilution in immunohistochemical analysis.

References

ab238585 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab238585.
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