Anti-Collagen I antibody (ab21286)

Rabbit polyclonal Collagen I antibody. Validated in WB, ELISA, IHC, RIA, ICC/IF and tested in Mouse. Cited in 86 publication(s). Independently reviewed in 12 review(s).

Publishing research using ab21286? Please let us know so that we can cite the reference in this datasheet.

ab21286 has been referenced in 94 publications.

  • Jiang B  et al. The inhibition of glycosaminoglycan incorporation influences the cell proliferation and cytodifferentiation in cultured embryonic mouse molars. J Mol Histol 50:11-19 (2019). PubMed: 30498999
  • Forrester A  et al. A selective ER-phagy exerts procollagen quality control via a Calnexin-FAM134B complex. EMBO J 38:N/A (2019). PubMed: 30559329
  • Morgoulis D  et al. sPIF promotes myoblast differentiation and utrophin expression while inhibiting fibrosis in Duchenne muscular dystrophy via the H19/miR-675/let-7 and miR-21 pathways. Cell Death Dis 10:82 (2019). PubMed: 30692507
  • Kamata M  et al. Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice. PLoS One 14:e0202842 (2019). PubMed: 30818366
  • Mohamad N  et al. In vivo evaluation of bacterial cellulose/acrylic acid wound dressing hydrogel containing keratinocytes and fibroblasts for burn wounds. Drug Deliv Transl Res 9:444-452 (2019). PubMed: 29302918
  • Bowers SLK  et al. Inhibition of fibronectin polymerization alleviates kidney injury due to ischemia-reperfusion. Am J Physiol Renal Physiol 316:F1293-F1298 (2019). PubMed: 31017009
  • Zhang S  et al. Osthole Ameliorates Renal Fibrosis in Mice by Suppressing Fibroblast Activation and Epithelial-Mesenchymal Transition. Front Physiol 9:1650 (2018). PubMed: 30524310
  • Li P  et al. Roles for HB-EGF in Mesenchymal Stromal Cell Proliferation and Differentiation During Skeletal Growth. J Bone Miner Res N/A:N/A (2018). PubMed: 30550637
  • Marques S  et al. Transcriptional Convergence of Oligodendrocyte Lineage Progenitors during Development. Dev Cell 46:504-517.e7 (2018). PubMed: 30078729
  • Pabón MA  et al. Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease. JCI Insight 3:N/A (2018). PubMed: 30232271
  • Dias DO  et al. Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury. Cell 173:153-165.e22 (2018). PubMed: 29502968
  • Mikamo M  et al. Inhibiting Skp2 E3 Ligase Suppresses Bleomycin-Induced Pulmonary Fibrosis. Int J Mol Sci 19:N/A (2018). PubMed: 29415439
  • Patra D  et al. Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open 7:N/A (2018). PubMed: 29437042
  • Liu H  et al. Isolation, culture and induced differentiation of rabbit mesenchymal stem cells into osteoblasts. Exp Ther Med 15:3715-3724 (2018). PubMed: 29581732
  • Stüdle C  et al. Spatially confined induction of endochondral ossification by functionalized hydrogels for ectopic engineering of osteochondral tissues. Biomaterials 171:219-229 (2018). PubMed: 29705655
  • Xia X  et al. Asiatic acid prevents the development of interstitial lung disease in a hypochlorous acid-induced mouse model of scleroderma. Oncol Lett 15:8711-8716 (2018). PubMed: 29805609
  • Bier A  et al. Placenta-derived mesenchymal stromal cells and their exosomes exert therapeutic effects in Duchenne muscular dystrophy. Biomaterials 174:67-78 (2018). PubMed: 29783118
  • Wang C  et al. Loss of Dnmt3b in Chondrocytes Leads to Delayed Endochondral Ossification and Fracture Repair. J Bone Miner Res 33:283-297 (2018). IHC ; Mouse . PubMed: 29024060
  • Liu YY  et al. Telomere shortening activates TGF-ß/Smads signaling in lungs and enhances both lipopolysaccharide and bleomycin-induced pulmonary fibrosis. Acta Pharmacol Sin N/A:N/A (2018). PubMed: 29925920
  • Eley L  et al. A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice. Elife 7:N/A (2018). PubMed: 29956664
  • Loh EYX  et al. Development of a bacterial cellulose-based hydrogel cell carrier containing keratinocytes and fibroblasts for full-thickness wound healing. Sci Rep 8:2875 (2018). IHC . PubMed: 29440678
  • Imamura M  et al. RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase. JCI Insight 3:N/A (2018). PubMed: 29415885
  • Guo S  et al. GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1. Cell Death Differ N/A:N/A (2018). PubMed: 29523871
  • Yoo SY  et al. Chimeric Adeno-Associated Virus-Mediated Cardiovascular Reprogramming for Ischemic Heart Disease. ACS Omega 3:5918-5925 (2018). PubMed: 30023931
  • Rajasekaran S  et al. Infectivity of adeno-associated virus serotypes in mouse testis. BMC Biotechnol 18:70 (2018). PubMed: 30384832
  • Zhang P  et al. Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene. Cell Death Dis 9:1145 (2018). PubMed: 30451833
  • Meng H  et al. Annexin A3 gene silencing promotes myocardial cell repair through activation of the PI3K/Akt signaling pathway in rats with acute myocardial infarction. J Cell Physiol N/A:N/A (2018). PubMed: 30456911
  • Shimizu Y  et al. Angiotensin II subtype 1a receptor signaling in resident hepatic macrophages induces liver metastasis formation. Cancer Sci 108:1757-1768 (2017). IHC-P ; Mouse . PubMed: 28660748
  • Comunanza V  et al. VEGF blockade enhances the antitumor effect of BRAFV600E inhibition. EMBO Mol Med 9:219-237 (2017). IF ; Human . PubMed: 27974353
  • Ritsma L  et al. Integrin ß1 activation induces an anti-melanoma host response. PLoS One 12:e0175300 (2017). IHC, ICC/IF ; Mouse, Human . PubMed: 28448494
  • Testa S  et al. Combination of biochemical and mechanical cues for tendon tissue engineering. J Cell Mol Med N/A:N/A (2017). IF ; Mouse . PubMed: 28470843
  • Bennett RG  et al. Serelaxin increases the antifibrotic action of rosiglitazone in a model of hepatic fibrosis. World J Gastroenterol 23:3999-4006 (2017). Histology, IHC ; Mouse . PubMed: 28652653
  • Tang J  et al. Potential therapeutic role of punicalagin against mechanical-trauma-induced stress urinary incontinence via upregulation of Nrf2 and TGF-ß1 signaling : Effect of punicalagin on mechanical trauma induced SUI. Int Urogynecol J 28:947-955 (2017). PubMed: 28168411
  • Tomczyk M  et al. Splenic Ly6C(hi) monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice. Basic Res Cardiol 112:39 (2017). PubMed: 28534119
  • Tang J  et al. Mechanism of Mechanical Trauma-Induced Extracellular Matrix Remodeling of Fibroblasts in Association with Nrf2/ARE Signaling Suppression Mediating TGF-ß1/Smad3 Signaling Inhibition. Oxid Med Cell Longev 2017:8524353 (2017). PubMed: 29109834
  • Nagao M  et al. Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis. Sci Rep 7:13027 (2017). PubMed: 29026147
  • Qian C  et al. Stage specific requirement of platelet-derived growth factor receptor-a in embryonic development. PLoS One 12:e0184473 (2017). PubMed: 28934221
  • Cho SJ  et al. Glucose Transporter 1-Dependent Glycolysis Is Increased during Aging-Related Lung Fibrosis, and Phloretin Inhibits Lung Fibrosis. Am J Respir Cell Mol Biol 56:521-531 (2017). PubMed: 27997810
  • Zhou VX  et al. Direct orthotopic implantation of hepatic organoids. J Surg Res 211:251-260 (2017). PubMed: 28501125
  • Anzai A  et al. The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes. J Exp Med 214:3293-3310 (2017). PubMed: 28978634
  • Hu K  et al. Cell autonomous ANTXR1-mediated regulation of extracellular matrix components in primary fibroblasts. Matrix Biol 62:105-114 (2017). PubMed: 28011198
  • Herrera C  et al. Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis. PLoS Negl Trop Dis 10:e0004599 (2016). PubMed: 27035343
  • Liu G  et al. Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases. JCI Insight 1:N/A (2016). PubMed: 27398409
  • Maruyama S  et al. Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture. EMBO Mol Med 8:949-66 (2016). WB . PubMed: 27234440
  • Nakamichi R  et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun 7:12503 (2016). WB . PubMed: 27527664
  • Xie T  et al. Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis. J Clin Invest 126:3063-79 (2016). PubMed: 27400124
  • Bianchi E  et al. Ghrelin ameliorates adhesions in a postsurgical mouse model. J Surg Res 201:226-34 (2016). PubMed: 26850207
  • Sager HB  et al. Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure. Circ Res 119:853-64 (2016). PubMed: 27444755
  • Kanisicak O  et al. Genetic lineage tracing defines myofibroblast origin and function in the injured heart. Nat Commun 7:12260 (2016). PubMed: 27447449
  • Marques S  et al. Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system. Science 352:1326-9 (2016). PubMed: 27284195
  • Li C  et al. RhoA determines lineage fate of mesenchymal stem cells by modulating CTGF-VEGF complex in extracellular matrix. Nat Commun 7:11455 (2016). IHC (PFA fixed) . PubMed: 27126736
  • Semeniak D  et al. Proplatelet formation is selectively inhibited by collagen type I through Syk-independent GPVI signaling. J Cell Sci 129:3473-84 (2016). PubMed: 27505889
  • Fransén-Pettersson N  et al. A New Mouse Model That Spontaneously Develops Chronic Liver Inflammation and Fibrosis. PLoS One 11:e0159850 (2016). IHC-P ; Mouse . PubMed: 27441847
  • Akashi K  et al. Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice. Arthritis Res Ther 18:113 (2016). IHC-P ; Mouse . PubMed: 27209208
  • Kelly KK  et al. Col1a1+ perivascular cells in the brain are a source of retinoic acid following stroke. BMC Neurosci 17:49 (2016). IHC-Fr ; Mouse . PubMed: 27422020
  • Ben Shoham A  et al. Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development 143:3933-3943 (2016). Electron Microscopy . PubMed: 27621060
  • Grandl G  et al. Depot specific differences in the adipogenic potential of precursors are mediated by collagenous extracellular matrix and Flotillin 2 dependent signaling. Mol Metab 5:937-47 (2016). PubMed: 27689006
  • Saito K  et al. Osteopontin Is Essential for Type I Collagen Secretion in Reparative Dentin. J Dent Res 95:1034-41 (2016). IHC ; Mouse . PubMed: 27126446
  • Mostofi S  et al. Effects of Corroded and Non-Corroded Biodegradable Mg and Mg Alloys on Viability, Morphology and Differentiation of MC3T3-E1 Cells Elicited by Direct Cell/Material Interaction. PLoS One 11:e0159879 (2016). WB, ICC ; Mouse . PubMed: 27459513
  • Goto K  et al. Intravenous Administration of Endothelial Colony-Forming Cells Overexpressing Integrin ß1 Augments Angiogenesis in Ischemic Legs. Stem Cells Transl Med 5:218-26 (2016). WB ; Mouse . PubMed: 26702126
  • Shanmugam VK  et al. Utility of a human-mouse xenograft model and in vivo near-infrared fluorescent imaging for studying wound healing. Int Wound J 12:699-705 (2015). PubMed: 24373153
  • Grimaldi A  et al. A Comprehensive Study of Soft Palate Development in Mice. PLoS One 10:e0145018 (2015). IF ; Mouse . PubMed: 26671681
  • Uslu B  et al. Differences between Solution and Membrane Forms of Chitosan on the In Vitro Activity of Fibroblasts. Balkan Med J 32:69-78 (2015). IHC-P ; Mouse . PubMed: 25759775
  • Cooley LF  et al. Increased B Cell ADAM10 in Allergic Patients and Th2 Prone Mice. PLoS One 10:e0124331 (2015). IHC ; Mouse . PubMed: 25933166
  • Li SF  et al. Regulation of bone formation by baicalein via the mTORC1 pathway. Drug Des Devel Ther 9:5169-83 (2015). ICC/IF ; Mouse . PubMed: 26392752
  • Grootaert MO  et al. Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy 11:2014-2032 (2015). ICC/IF ; Mouse . PubMed: 26391655
  • Palumbo-Zerr K  et al. Orphan nuclear receptor NR4A1 regulates transforming growth factor-ß signaling and fibrosis. Nat Med 21:150-8 (2015). PubMed: 25581517
  • Hilgendorff A  et al. Lung matrix and vascular remodeling in mechanically ventilated elastin haploinsufficient newborn mice. Am J Physiol Lung Cell Mol Physiol 308:L464-78 (2015). WB, IHC-P ; Mouse . PubMed: 25539853
  • McDonald LT  et al. Hematopoietic stem cell-derived cancer-associated fibroblasts are novel contributors to the pro-tumorigenic microenvironment. Neoplasia 17:434-48 (2015). Mouse . PubMed: 26025666
  • McDonald LT  et al. Hematopoietic Origin of Murine Lung Fibroblasts. Stem Cells Int 2015:159713 (2015). Mouse . PubMed: 26185498
  • Mishra S  et al. Estrogen and estrogen receptor alpha promotes malignancy and osteoblastic tumorigenesis in prostate cancer. Oncotarget 6:44388-402 (2015). IHC . PubMed: 26575018
  • Besschetnova TY  et al. Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. Matrix Biol 42:56-73 (2015). IHC ; Mouse . PubMed: 25572963
  • Sun F & Hu K Krüppel-Like Factor 4 Inhibits the Transforming Growth Factor-ß1-Promoted Epithelial-to-Mesenchymal Transition via Downregulating Plasminogen Activator Inhibitor-1 in Lung Epithelial Cells. Dis Markers 2015:473742 (2015). WB . PubMed: 26839446
  • Yu ML  et al. The Effects of TiO2 Nanodot Films with RGD Immobilization on Light-Induced Cell Sheet Technology. Biomed Res Int 2015:582359 (2015). WB . PubMed: 26417596
  • Suga H  et al. Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing. Stem Cells 32:1347-60 (2014). WB ; Mouse . PubMed: 24446236
  • Bility MT  et al. Hepatitis B virus infection and immunopathogenesis in a humanized mouse model: induction of human-specific liver fibrosis and M2-like macrophages. PLoS Pathog 10:e1004032 (2014). IHC-P ; Mouse . PubMed: 24651854
  • Kach J  et al. Antifibrotic effects of noscapine through activation of prostaglandin E2 receptors and protein kinase A. J Biol Chem 289:7505-13 (2014). IHC (PFA fixed) ; Human . PubMed: 24492608
  • Lee JJ  et al. Stromal response to Hedgehog signaling restrains pancreatic cancer progression. Proc Natl Acad Sci U S A 111:E3091-100 (2014). PubMed: 25024225
  • Oujo B  et al. L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction. PLoS One 9:e110365 (2014). IHC, WB ; Mouse . PubMed: 25313562
  • Hilgendorf I  et al. Ly-6Chigh monocytes depend on Nr4a1 to balance both inflammatory and reparative phases in the infarcted myocardium. Circ Res 114:1611-22 (2014). IHC-Fr ; Mouse . PubMed: 24625784
  • Breynaert C  et al. Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease. PLoS One 8:e68876 (2013). IHC ; Mouse . PubMed: 23894361
  • Perry SW  et al. Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells. BMC Cancer 13:411 (2013). IHC ; Mouse . PubMed: 24010522
  • Folgosa L  et al. Disturbed follicular architecture in B cell A disintegrin and metalloproteinase (ADAM)10 knockouts is mediated by compensatory increases in ADAM17 and TNF-a shedding. J Immunol 191:5951-8 (2013). Mouse . PubMed: 24227779
  • Hanson KP  et al. Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A 19:1132-43 (2013). IHC . PubMed: 23273220
  • Hosaka K  et al. Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis. Nat Commun 4:2129 (2013). PubMed: 23831851
  • Lopes J  et al. Type VIII collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis. Am J Pathol 182:2241-53 (2013). IHC . PubMed: 23567639
  • Danzaki K  et al. Interleukin-17A deficiency accelerates unstable atherosclerotic plaque formation in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 32:273-80 (2012). PubMed: 22116098
  • Haist V  et al. Distinct spatio-temporal extracellular matrix accumulation within demyelinated spinal cord lesions in Theiler's murine encephalomyelitis. Brain Pathol 22:188-204 (2012). IHC-P ; Mouse . PubMed: 21767322
  • Schwarz MA  et al. Lung self-assembly is modulated by tissue surface tensions. Am J Respir Cell Mol Biol 44:682-91 (2011). PubMed: 20616358
  • Lovgren AK  et al. ß-arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix. Sci Transl Med 3:74ra23 (2011). WB ; Mouse . PubMed: 21411739
  • Hattori T  et al. SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development 137:901-11 (2010). IHC-P ; Mouse . PubMed: 20179096
  • Niedermeier M  et al. CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes. Proc Natl Acad Sci U S A 106:17892-7 (2009). ELISA, IHC-Fr ; Mouse . PubMed: 19815530
  • Mukherjee S  et al. Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. J Clin Invest 118:491-504 (2008). Mouse . PubMed: 18219387
  • El Shikh ME  et al. Follicular dendritic cells stimulated by collagen type I develop dendrites and networks in vitro. Cell Tissue Res 329:81-9 (2007). PubMed: 17372768

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