Recombinant
RabMAb

Recombinant Anti-Complement factor B antibody [EPR9287(B)] (ab140647)

Overview

  • Product name

    Anti-Complement factor B antibody [EPR9287(B)]
    See all Complement factor B primary antibodies
  • Description

    Rabbit monoclonal [EPR9287(B)] to Complement factor B
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC/IF or IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • Positive control

    • Human serum and Human plasma.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR9287(B)
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab140647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 86 kDa.
  • Application notes
    Is unsuitable for ICC/IF or IHC-P.
  • Target

    • Relevance

      Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
    • Cellular localization

      Plasma membrane and Secreted
    • Database links

    • Alternative names

      • C3/C5 convertase antibody
      • Complement factor B antibody
      • Glycine-rich beta glycoprotein antibody
      • PBF2 antibody
      • Properdin factor B antibody
      see all

    Images

    • All lanes : Anti-Complement factor B antibody [EPR9287(B)] (ab140647) at 1/1000 dilution

      Lane 1 : Human serum
      Lane 2 : Human plasma

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP conjugated goat anti-rabbit at 1/2000 dilution

      Predicted band size: 86 kDa

    References

    ab140647 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab140647.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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