Recombinant
RabMAb

Recombinant Anti-Complement factor B antibody [EPR9288(B)] - BSA and Azide free (ab248646)

Overview

  • Product name

    Anti-Complement factor B antibody [EPR9288(B)] - BSA and Azide free
    See all Complement factor B primary antibodies
  • Description

    Rabbit monoclonal [EPR9288(B)] to Complement factor B - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Complement factor B aa 750-850 (C terminal). The exact sequence is proprietary.
    Database link: P00751

  • General notes

    Ab248646 is the carrier-free version of ab133765. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Dissociation constant (KD)

    KD = 1.43 x 10 -10 M
    Learn more about KD
  • Concentration information loading...
  • Purity

    Affinity purified
  • Clonality

    Monoclonal
  • Clone number

    EPR9288(B)
  • Isotype

    IgG

Applications

Our Abpromise guarantee covers the use of ab248646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 95, 60 kDa (predicted molecular weight: 86 kDa).
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Relevance

      Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
    • Cellular localization

      Plasma membrane and Secreted
    • Database links

    • Alternative names

      • C3/C5 convertase antibody
      • Complement factor B antibody
      • Glycine-rich beta glycoprotein antibody
      • PBF2 antibody
      • Properdin factor B antibody
      see all

    References

    ab248646 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab248646.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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