Information and products associated with novel coronavirus research
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Overview
- Background to coronaviruses
- Products to support coronavirus research
- Antibodies and proteins specific for human coronaviruses
- ACE2 products: antibodies, ELISA kits, proteins, and KO cell lines
- ACE2 related targets
- Digital spatial profiling of proteins in COVID-19 tissue samples
- Rapid SARS-CoV-2 lateral flow assays
Coronaviruses, named after their crown-like shape, were first identified in the 1960s and are associated with a range of respiratory symptoms. Cases such as Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 1 and 2 (SARS-CoV-1 and -2) can cause aggravated symptoms in humans and can lead to pneumonia, severe acute respiratory syndrome, and death1,2 . SARS-CoV-2, which causes the COVID-19 disease, is the latest coronavirus strain to be identified.
Products to support coronavirus research
Abcam offers a variety of tools used to help understand and accelerate infectious disease research, including SARS-CoV-2, the coronavirus that causes COVID-19. To help researchers navigate quickly to relevant products, listed below are antibodies and proteins specific for the detection and analysis of human coronaviruses.
Our product range for cytokine detection and research of SARS-CoV-2 can be found here.
If there is a product you need for COVID-19-related research that is not listed here, please contact us and we may be able to help.
Antibodies and proteins specific for human coronaviruses
| Name | abID | Application |
| Anti-SARS spike glycoprotein antibody [1A9] | ab273433 | ELISA, WB, ICC/IF, Flow Cyt, IP |
| Anti-SARS spike glycoprotein antibody [3A2] - Coronavirus | ab272420 | WB, ICC/IF, Flow Cyt |
| Anti-SARS-CoV-2 spike glycoprotein antibody - Coronavirus | ab272504 | ELISA |
Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [CR3022] | ab273073 | Neutralizing, ELISA |
| Recombinant Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [CR3022] - Chimeric | ab273074 | Neutralizing, ELISA |
Recombinant Anti-SARS-CoV-2 Spike Ectodomain antibody [CV1] | I-ELISA | |
Anti-SARS-CoV-2 Spike RBD antibody [CV30] | I-ELISA | |
Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein S1 (His tag) | SDS-PAGE | |
Recombinant Human coronavirus SARS-CoV-2 spike glycoprotein (Mutant) | SDS-PAGE | |
Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein S2 - mutant (His tag) | ab274366 | SDS-PAGE |
Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein RBD (His tag) | I-ELISA | |
| Anti-SARS nucleocapsid protein antibody [6H3] | ab273434 | ELISA, WB, ICC/IF, Flow Cyt, IP |
| Anti-SARS-CoV-2 nucleocapsid protein antibody | WB, IHC | |
| Anti-SARS-CoV-2 nucleocapsid protein antibody [1A6] - Chimeric | ELISA, WB | |
| Recombinant Human coronavirus SARS-CoV-2 nucleocapsid protein (His tag) | ab273530 | ELISA, WB |
| Anti-SARS E antibody | ab22055 | WB |
| Anti-SARS-CoV-2 envelope protein antibody - Coronavirus | ab272503 | ELISA |
| Human coronavirus SARS-CoV-2 envelope protein peptide | BL |
See a complete list of coronavirus-specific products.
SARS-CoV-2 ELISA kits
Sandwich-based ELISAs for the quantitative measurement of COVID-19 antigens in serum samples.
ACE2 products: antibodies, ELISA kits, proteins, and KO cell lines
| Name | abID | Application | Species |
| Human ACE2 knockout HepG2 cell line | ab273733 | WB | Human |
| Human ACE2 knockout HepG2 cell lysate | ab275495 | WB | Human |
| Human ACE2 ELISA Kit | ab235649 | ELISA | Human |
| Human ACE2 Antibody Pair - BSA and Azide free | ab244135 | ELISA | Human |
| Recombinant Anti-ACE2 antibody [EPR4435(2)] | ab108252 | IHC-P, IP, WB | Mouse, Rat, Human |
| Recombinant Anti-ACE2 antibody [EPR4435(2)] - BSA and Azide free | ab239924 | IHC-P, IP, WB | Mouse, Rat, Human |
| Anti-ACE2 antibody | ab15348 | IHC-Fr, WB, IHC-P | Cat, Human, Ferret, Macaque monkey, Bat |
| Recombinant Human ACE2 protein | ab151852 | SDS-PAGE, HPLC | Human |
| Recombinant Human ACE2 protein (Fc Chimera) | ab273687 | SDS-PAGE, HPLC, ELISA | Human |
| Recombinant Human ACE2 (mutated H374 N + H378 N) protein (Fc Chimera) | ab273885 | SDS-PAGE, HPLC, ELISA | Human |
Anti-ACE2 antibody [EPR4436] Anti-ACE2 antibody [EPR4436] | ab108209 | WB, IP, IHC-P | Human |
| DX600 ACE2 inhibitor | ab273525 |
See a complete list of products targeting ACE2 receptors.
ACE2 related targets
Please find below a list of targets that may help to accelerate your research on ACE-2 receptors.
| Name | AbID | Application | Species |
| Recombinant human TMPRSS2 protein | ab112364 | SDS-PAGE | Human |
| Anti-TMPRSS2 antibody [EPR3862] | ab109131 | ICC/IF, WB, IHC-P | Mouse, Rat, Human |
| Recombinant anti-TMPRSS2 antibody [EPR3861] | ab92323 | WB, IHC-P | Mouse, Rat, Human, Cynomolgus monkey, Rhesus monkey, Common marmoset |
| Recombinant anti-DPP4 antibody [EPR20819] | ab215711 | WB, IHC-P | Human |
| Recombinant anti-DPP4 antibody [EPR18215] | ab187048 | WB, IHC-P, IHC-Fr | Mouse, Rat |
| Human DPP4 ELISA kit | ab252365 | ELISA | Human |
| Recombinant anti-MCP1 antibody [EPR21025] | ab214819 | WB, ICC/IF, Flow Cyt, IP (unsuitable for IHC-P) | Human |
| Human MCP-1 ELISA kit | ab179886 | ELISA | Human |
| Recombinant anti-CD13 antibody [EPR4058] | ab108310 | WB, IHC-P, ICC/IF (Unsuitable for Flow Cyt, IP) | Mouse, Rat, Human |
| Human CD13 ELISA kit | ab239427 | ELISA | Human |
| Human ANPEP (CD13) knockout THP-1 cell line | ab273759 | Flow Cyt, WB, ICC | Human |
| Human ANPEP (CD13) knockout THP-1 cell lysate | ab275505 | WB | Human |
More KO cell lines for key targets in the COVID-19 immune response, including IL-6 and TNF-alpha, can be found in our KO cell line catalog.
Digital spatial profiling of proteins in COVID-19 tissue samples
In the study of SARS-CoV-2 and COVID-19, rapid and reproducible spatial analysis of clinically relevant tissue samples is challenging due to the fixation processes required to prevent disease transmission.
Developed in partnership with NanoString, the COVID-19 GeoMx-formatted Antibody Panel provides a custom panel which will be run with the GeoMx Immune Profiling Core to enable spatial analysis of 96 proteins involved in the immune response to SARS-CoV-2 infection.
This new panel further expands the protein content available on the GeoMx® Digital Spatial Profiler to enable high-plex analysis of key biological pathways mapped to specific regions within infected tissues. The data generated demonstrates the application of this new tool in SARS-CoV-2 formalin-fixed paraffin-embedded (FFPE) tissue samples and how it can be used to better understand the processes underlying infection, pathogenesis and therapeutic response.
This is another solution to support the study of the immune response in COVID-19 disease research.
| Product | abID |
| COVID-19 GeoMx-formatted Antibody Panel |
Rapid SARS-CoV-2 lateral flow assays
See below our rapid coronavirus lateral flow assays that enable the detection of novel coronavirus IgG or IgM antibodies in 8-10 minutes.
| Name | abID | Sample type | Detects | Time to results |
Novel Coronavirus IgG Antibody Detection Kit | ab272243 | Human serum, plasma, whole blood | Coronavirus N-Protein IgG antibodies | 8-10 min |
Novel Coronavirus IgM Antibody Detection Kit | ab272244 | Human serum, plasma, whole blood | Coronavirus N-protein IgM antibodies | 8-10 min |
See our serologic ELISA kits for the detection of antibodies to SARS-CoV-2.
Abcam’s products are intended for research use only, not for use in diagnostic, therapeutic or any other purposes. If you are interested in the commercial use of our products, please connect with us at partnerships@abcam.com.
References
1. https://www.who.int/ith/diseases/sars/en/
2. https://www.who.int/emergencies/mers-cov/en/