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Supporting our customers and employees during the COVID-19 pandemic. Read more

Information and products associated with novel coronavirus research

Related

  • COVID-19 cytokine products
    • SimpleStep ELISA®: accuracy and speed when assessing COVID-19
      • SARS-CoV-2 structure and cell entry
        • Blood-based biomarkers for COVID-19
          • Tips to maximize your bench time
            • SARS-CoV-2 spike protein antibody in research
              • Maximize research efficiency on your return to the lab

                ​​Overview 

                • Background to coronaviruses
                • Products to support coronavirus research
                • Antibodies and proteins specific for human coronaviruses
                • ACE2 products: antibodies, ELISA kits, proteins, and KO cell lines
                • ACE2 related targets
                • Digital spatial profiling of proteins in COVID-19 tissue samples
                • Rapid SARS-CoV-2 lateral flow assays

                ​​Background to coronaviruses​​

                ​​Coronaviruses, named after their crown-like shape, were first identified in the 1960s and are associated with a range of respiratory symptoms. Cases such as Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome coronavirus 1 and 2 (SARS-CoV-1 and -2) can cause aggravated symptoms in humans and can lead to pneumonia, severe acute respiratory syndrome, and death1,2 . SARS-CoV-2, which causes the COVID-19 disease, is the latest coronavirus strain to be identified.  

                Products to support coronavirus research

                Abcam offers a variety of tools used to help understand and accelerate infectious disease research, including SARS-CoV-2, the coronavirus that causes COVID-19. To help researchers navigate quickly to relevant products, listed below are antibodies and proteins specific for the detection and analysis of human coronaviruses. 

                Our product range for cytokine detection and research of SARS-CoV-2 can be found here. 

                If there is a product you need for COVID-19-related research that is not listed here, please contact us and we may be able to help.

                Antibodies and proteins specific for human coronaviruses

                NameabIDApplication
                Anti-SARS spike glycoprotein antibody [1A9]ab273433ELISA, WB, ICC/IF, Flow Cyt, IP
                Anti-SARS spike glycoprotein antibody [3A2] - Coronavirusab272420WB, ICC/IF, Flow Cyt
                Anti-SARS-CoV-2 spike glycoprotein antibody - Coronavirusab272504ELISA

                Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [CR3022] 

                ab273073Neutralizing, ELISA
                Recombinant Anti-SARS-CoV-2 Spike Glycoprotein S1 antibody [CR3022] - Chimericab273074Neutralizing, ELISA

                Recombinant Anti-SARS-CoV-2 Spike Ectodomain antibody [CV1]

                ab277512

                I-ELISA

                Anti-SARS-CoV-2 Spike RBD antibody [CV30]

                ab277513

                I-ELISA

                Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein S1 (His tag)

                ab275927


                SDS-PAGE

                Recombinant Human coronavirus SARS-CoV-2 spike glycoprotein (Mutant)

                ab274432

                SDS-PAGE

                Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein S2 - mutant (His tag)

                ab274366SDS-PAGE

                Recombinant Human coronavirus SARS-CoV-2 Spike Glycoprotein RBD (His tag)

                ab275986

                I-ELISA
                Anti-SARS nucleocapsid protein antibody [6H3]ab273434ELISA, WB, ICC/IF, Flow Cyt, IP
                Anti-SARS-CoV-2 nucleocapsid protein antibody

                ab273167

                WB, IHC
                Anti-SARS-CoV-2 nucleocapsid protein antibody [1A6] - Chimeric

                ab272852

                ELISA, WB
                Recombinant Human coronavirus SARS-CoV-2 nucleocapsid protein (His tag)ab273530ELISA, WB
                Anti-SARS E antibodyab22055WB
                Anti-SARS-CoV-2 envelope protein antibody - Coronavirusab272503ELISA
                Human coronavirus SARS-CoV-2 envelope protein peptide

                ab273064

                BL

                See a complete list of coronavirus-specific products.


                SARS-CoV-2 ELISA kits

                Sandwich-based ELISAs for the quantitative measurement of COVID-19 antigens in serum samples.

                ProductabID
                COVID-19 N-protein ELISA Kitab274341
                COVID-19 Spike Protein ELISA Kitab274342


                ACE2 products: antibodies, ELISA kits, proteins, and KO cell lines

                NameabIDApplicationSpecies
                Human ACE2 knockout HepG2 cell line
                ab273733

                WB

                Human
                Human ACE2 knockout HepG2 cell lysate
                ab275495

                WB

                Human
                Human ACE2 ELISA Kitab235649ELISAHuman
                Human ACE2 Antibody Pair - BSA and Azide freeab244135ELISAHuman
                Recombinant Anti-ACE2 antibody [EPR4435(2)]ab108252IHC-P, IP, WBMouse, Rat, Human
                Recombinant Anti-ACE2 antibody [EPR4435(2)] - BSA and Azide free
                ab239924

                IHC-P, IP, WB

                Mouse, Rat, Human
                Anti-ACE2 antibodyab15348IHC-Fr, WB, IHC-PCat, Human, Ferret, Macaque monkey, Bat
                Recombinant Human ACE2 proteinab151852 SDS-PAGE, HPLCHuman
                Recombinant Human ACE2 protein (Fc Chimera)ab273687SDS-PAGE, HPLC, ELISAHuman
                Recombinant Human ACE2 (mutated H374 N + H378 N) protein (Fc Chimera)ab273885SDS-PAGE, HPLC, ELISAHuman
                Anti-ACE2 antibody [EPR4436]
                Anti-ACE2 antibody [EPR4436]
                ab108209WB, IP, IHC-PHuman
                DX600 ACE2 inhibitorab273525

                See a complete list of products targeting ACE2 receptors.

                ACE2 related targets 

                Please find below a list of targets that may help to accelerate your research on ACE-2 receptors.

                NameAbIDApplicationSpecies
                Recombinant human TMPRSS2 proteinab112364SDS-PAGEHuman
                Anti-TMPRSS2 antibody [EPR3862]ab109131ICC/IF, WB, IHC-PMouse, Rat, Human
                Recombinant anti-TMPRSS2 antibody [EPR3861]ab92323WB, IHC-PMouse, Rat, Human, Cynomolgus monkey, Rhesus monkey, Common marmoset
                Recombinant anti-DPP4 antibody [EPR20819]ab215711WB, IHC-PHuman
                Recombinant anti-DPP4 antibody [EPR18215]ab187048WB, IHC-P, IHC-FrMouse, Rat
                Human DPP4 ELISA kitab252365ELISAHuman
                Recombinant anti-MCP1 antibody [EPR21025]ab214819WB, ICC/IF, Flow Cyt, IP (unsuitable for IHC-P)Human
                Human MCP-1 ELISA kitab179886ELISAHuman
                Recombinant anti-CD13 antibody [EPR4058]ab108310WB, IHC-P, ICC/IF (Unsuitable for Flow Cyt, IP)Mouse, Rat, Human
                Human CD13 ELISA kitab239427ELISAHuman
                Human ANPEP (CD13) knockout THP-1 cell lineab273759
                Flow Cyt, WB, ICC
                Human
                Human ANPEP (CD13) knockout THP-1 cell lysate
                ab275505
                WBHuman

                More KO cell lines for key targets in the COVID-19 immune response, including IL-6 and TNF-alpha, can be found in our KO cell line catalog.

                Digital spatial profiling of proteins in COVID-19 tissue samples

                In the study of SARS-CoV-2 and COVID-19, rapid and reproducible spatial analysis of clinically relevant tissue samples is challenging due to the fixation processes required to prevent disease transmission. 

                Developed in partnership with NanoString, the COVID-19 GeoMx-formatted Antibody Panel provides a custom panel which will be run with the GeoMx Immune Profiling Core to enable spatial analysis of 96 proteins involved in the immune response to SARS-CoV-2 infection. 

                This new panel further expands the protein content available on the GeoMx® Digital Spatial Profiler to enable high-plex analysis of key biological pathways mapped to specific regions within infected tissues. The data generated demonstrates the application of this new tool in SARS-CoV-2 formalin-fixed paraffin-embedded (FFPE) tissue samples and how it can be used to better understand the processes underlying infection, pathogenesis and therapeutic response.

                This is another solution to support the study of the immune response in COVID-19 disease research.

                ProductabID
                COVID-19 GeoMx-formatted Antibody Panel

                ab273594


                ​Rapid SARS-CoV-2 lateral flow assays

                See below our rapid coronavirus lateral flow assays that enable the detection of novel coronavirus IgG or IgM antibodies in 8-10 minutes.

                NameabIDSample typeDetectsTime to results

                Novel Coronavirus IgG Antibody Detection Kit


                ab272243
                Human serum, plasma, whole bloodCoronavirus N-Protein IgG antibodies8-10 min

                Novel Coronavirus IgM Antibody Detection Kit

                ab272244Human serum, plasma, whole bloodCoronavirus N-protein IgM antibodies8-10 min

                See our serologic ELISA kits for the detection of antibodies to SARS-CoV-2.

                Abcam’s products are intended for research use only, not for use in diagnostic, therapeutic or any other purposes. If you are interested in the commercial use of our products, please connect with us at partnerships@abcam.com.


                References

                1. https://www.who.int/ith/diseases/sars/en/

                2. https://www.who.int/emergencies/mers-cov/en/







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