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This Product is provided by Bit Bio Ltd (Bit Bio) in partnership with Abcam plc (Abcam) under license from iPS Academia Japan, TET Systems GmbH, ERS Genomics Limited and Sigma-Aldrich Co. LLC.
Use of the Product is restricted to the terms contained within the individual Limited Use License Notices from each of the Licensors as set out below, and also by the general restriction that the User must only use the Product, Progeny, any Modifications of the Product and any Unmodified Derivatives of the Product in the Field.
The following Definitions apply to all Limited Use License Notices.
Field: Internal research use only. No Commercial Use is allowed.
Commercial Use: Any and all uses of the Product, Progeny, Modifications or Unmodified Derivatives thereof, by a party for monetary or other consideration and can include, but is not limited to use in:
(i) Manufacture of a Product;
(ii) Sale of a Product, Progeny, Modifications or Unmodified Derivatives thereof, whether or not such sale is limited for use in research;
(iii) Provision of a service to a third party;
(iv) Use in any diagnostic, preventative, or therapeutic application;
(v) Use in any veterinary, livestock or agricultural application; and
(vi) Use in later stage development of therapeutics, diagnostics, prophylactics (e.g., hit-to-lead, lead optimization).
Product: Cells which are differentiated from human iPS cells by Bit Bio Ltd., and which Bit Bio Ltd. sells, or are sold on behalf of Bit Bio Ltd. by a distributor
Progeny: Any unmodified descendant form of the Product
Modifications: Any modifications of the Product
Unmodified Derivatives: Any substances created by the User that constitute an unmodified functional subunit or product expressed by the Product
User: The person or entity who purchased the Product(s) from Abcam in partnership with Bit Bio.
The Product is sold by Abcam in partnership with Bit Bio under license from iPS Academia Japan, Inc (iPS-AJ). The Product is covered by one or more claims of issued patents and pending patent applications, including: U.S. Patent Nos. 8,048,999, 8,058,065, 8,129,187 and 8,278,104 and foreign counterparts thereof, including their divisions, continuations, extensions, substitutions, and those claiming priority therefrom or those claiming the same priorities therein.
The use of this Product is strictly limited to User’s own internal research as described in the iPS-AJ User Restrictions Notice set out below:
This Product contains the Tetracycline controllable expression system (the "Tet Technology"). The Tet Technology IP portfolio is proprietary to TET Systems GmbH & Co. KG (''TET Systems") and comprises a series of patents including U.S. patents 8,383,364, 9,181,556, European Patents EP 1954811, 2352833 and corresponding patent claims outside these regions. The purchaser of the Product (i.e. the User) is granted an automatic license to use the Tet Technology in the Field and excludes the right to transfer or sell the Product, the Tet Technology or its component parts to third parties. Users whose research using the Product is sponsored by for-profit organizations, which shall receive ownership to any data or results stemming from the sponsored research, shall need a license agreement from TET Systems in order to use this Product.
All Users of the Product acknowledge that the Tet Technology is experimental in nature. TET Systems makes no warranties, express or implied or of any kind, and hereby disclaims any warranties, representations, or guarantees of any kind as to the Tet Technology, patents, or products.
Under the terms specified in the Limited Use License all Users of this Product that do not have a license from TET Systems will be restricted to the purchase of less than 10 units of Product per annum. If the User is purchasing more than 10 units of Product per annum, a TET license will be required from TET Systems GmbH & Co. KG - please contact Abcam.
CRISPR Non-Exclusive License Agreement
Certain commercial entities and/or activities performed at commercial entities may require additional contract rights from ERS Genomics Limited which are not granted through the purchase of this product. For additional information please see www.ersgenomics.com/research-products.php.
The User (purchaser) receives a non-exclusive, non-transferable right to use the Product, Progeny, Modifications and Unmodified Derivatives for RESEARCH USE ONLY, which, subject to the exclusions below, includes use to discover and develop any product, including therapeutic products, which may then be sold to third parties, provided, however, that such products do not incorporate the Product, Progeny, Modifications, or Unmodified Derivatives.
For clarity, transfer of materials or provision of services by not for profit or academic core labs to their internal clients shall not constitute Commercial Use.
Except for the rights granted herein, any and all rights to the Product, Progeny, Modifications or Unmodified Derivatives thereof, shall remain in Bit Bio Ltd. No ownership rights are transferred.
The User shall have no right to assign the rights granted herein to third parties. The Product, Progeny, Modifications or Unmodified Derivatives thereof, must at all times remain in the possession of the User, except for a transfer to a scientific collaborator or to a service provider, to perform services, solely on behalf of the User.
ZFN License Agreement
This Product and its use are the subject of one or more of the following patents controlled by Sangamo BioSciences, Inc.: U.S. Patent Nos. 6,534,261, 6,607,882, 6,746,838, 6,794,136, 6,824,978, 6,866,997,
6,933,113, 6,979,539, 7,013,219, 7,030,215, 7,220,719, 7,241,573, 7,241,574, 7,585,849, 7,595,376,
6,903,185, 6,479,626, US20030232410, US20090203140 and corresponding foreign patent applications and patents.
BEFORE OPENING OR USING THIS PRODUCT, PLEASE READ THE TERMS AND CONDITIONS SET FORTH IN THIS LICENSE AGREEMENT. YOUR USE OF THIS PRODUCT SHALL CONSTITUTE ACKNOWLEDGMENT AND ACCEPTANCE OF THESE TERMS AND CONDITIONS.
The purchase of this Product conveys to the User, the non-transferable right to use the purchased Product in the Field. If you wish to use this Product for any purpose other than Licensed Research Use, you must first obtain an appropriate license from Sigma-Aldrich Co. LLC