Patents

Granted Patents

Country

Application No.

Filing Date

Patent No.

Grant Date

AU

2013266968

15 Mar 2013

AU 2013266968 B2

07 Dec 2017

CN

201380038920.6

15 Mar 2013

CN 104854241 B

14 Jul 2017

EP

13793997.1

15 Mar 2013

EP 2800811 B1

10 May 2017

EP

17163434.8

15 Mar 2013

EP 3241902 B1

28 Feb 2018

EP

18152360.6

15 Mar 2013

EP 3401400 B1

03 Apr 2019

GB

1420270.9

15 Mar 2013

GB 2518764 C

02 Mar 2016

GB

1601071.2

15 Mar 2013

GB 2537000 B

08 Mar 2017

HK

15106335.4

03 Jul 2015

HK 1207107 B

25 Aug 2017

HK

15112610.8

23 Dec 2015

HK 1211978 B

04 May 2018

HK

17103002.1

03 Jul 2015

HK 1230233 B

01 Jun 2018

JP

20150514015

15 Mar 2013

JP 6343605 B

25 May 2018

MX

20140014477

15 Mar 2013

MX 349744 B

10 Aug 2017

NZ

714353

15 Mar 2013

NZ 714353 B2

29 Aug 2017

SG

11201407702

15 Mar 2013

SG 11201407702X

20 Mar 2017

SG

10201701800Y

15 Mar 2013

SG 10201701800Y

21 Nov 2018

TN

2014/0493

25 Nov 2014

TN 24223

03 Jun 2016

UA

A201413835

15 Mar 2013

UA 118014

12 Nov 2018

US

13/842,859

15 Mar 2013

US 10266850 B2

23 Apr 2019

US

14/685,502

13 Apr 2015

US 10000772 B2

19 Jun 2018

US

14/942,782

16 Nov 2015

US 10227611 B2

12 Mar 2019

US

15/138,604

26 Apr 2016

US 10113167 B2

30 Oct 2018

ZA

2014/07881

29 Oct 2014

ZA 2014/07881

31 Jan 2018

DE

2020132012240.4

15 Mar 2013

DE 202013012240 U1

02 Feb 2016

DE

2020132012241.2

15 Mar 2013

DE 202013012241 U1

18 Jan 2016

DE

2020132012242.0

15 Mar 2013

DE 202013012242 U1

02 Feb 2016

Patent Applications

Country

Application No.

Filing Date

Publication No.

Publication Date

PCT

PCT/US2013/032589

15 Mar 2013

WO 2013/176772 A1

28 Nov 2013

AE

P1296/2014

25 Nov 2014

AU

2017225060

07 Sep 2017

AU 2017225060 A1

28 Sep 2017

AU

2019201850

18 Mar 2019

BR

1120140294410

15 Mar 2013

BR 1120140294410 A2

27 Jun 2017

CA

2872241

15 Mar 2013

CA 2872241 A1

28 Nov 2013

CL

2014003208

25 Nov 2014

CL 2014003208 A1

19 Jun 2015

CN

201710585690.5

15 Mar 2013

CN 107603976 A

19 Jan 2018

CO

20140259531

25 Nov 2014

CO 7151523 A2

29 Dec 2014

CR

20140538

24 Nov 2014

CR 20140538 A

18 Feb 2015

DZ

140780

22 Dec 2014

EA

201401319

15 Mar 2013

EA 201401319 A1

29 May 2015

EC

IEPI-2014-28704

15 Mar 2013

30 Oct 2015

EG

PCT1887/2014

15 Mar 2013

EP

19157590.1

15 Mar 2013

GB

1511669.2

15 Mar 2013

GB 201511669 D0

19 Aug 2015

GE

AP2013013674

15 Mar 2013

HK

15104473.1

12 May 2015

HK 1204003 A1

06 Nov 2015

HK

19119875.3

22 Feb 2019

ID

P00201407783

10 Dec 2014

2016/03367

13 May 2016

IL

235461

15 Mar 2013

31 Dec 2014

IL

261563

15 Mar 2013

31 Oct 2018

IL

261565

15 Mar 2013

31 Oct 2018

IL

261566

15 Mar 2013

31 Oct 2018

IL

261567

15 Mar 2013

31 Oct 2018

IL

261568

15 Mar 2013

31 Oct 2018

IL

261569

15 Mar 2013

31 Oct 2018

IL

261570

15 Mar 2013

31 Oct 2018

IN

2995/KOLNP/2014

15 Mar 2013

2995/KOLNP/2014 A

04 Dec 2015

JP

2018-097369

21 May 2018

2018-138054

06 Sep 2018

KE

P/2014/002178

25 Nov 2014

KR

1020147036096

15 Mar 2013

KR 1020150016588 A

12 Feb 2015

KR

1020177034069

15 Mar 2013

KR 1020170134766 A

06 Dec 2017

KS

P/2017/000022

15 Mar 2013

LY

4958/2014

15 Mar 2013

MA

37663

15 Mar 2013

MA 37663 A1

31 May 2017

MX

2017010309

15 Mar 2013

MX

2019001995

15 Mar 2013

MY

PI2014003102

15 Mar 2013

MY

PI2018700285

15 Mar 2013

NZ

701326

15 Mar 2013

NZ

728024

15 Mar 2013

NZ 728024 A

27 Jan 2017

NZ

730667

15 Mar 2013

NZ 730667 A1

31 Mar 2017

OM

P/2014/00268

25 Nov 2014

PA

90441-01

25 Nov 2014

12 Sep 2016

PE

002211-2014/DIN

15 Mar 2013

PE 03362015 A1

25 Mar 2015

PH

12014502574

19 Nov 2014

PH 12014502574 A1

21 Jan 2015

QA

20141100400

15 Mar 2013

SG

10201809817U

15 Mar 2013

SG 10201809817U A

28 Dec 2018

SY

2014120156

15 Mar 2013

TH

1401007063

15 Mar 2013

TH 173084

15 Feb 2018

UA

A201808549

07 Aug 2018

US

61/652,086

25 May 2012

US

61/716,256

19 Oct 2012

US

61/757,640

28 Jan 2013

US

61/765,576

15 Feb 2013

US

14/403,475

24 Nov 2014

US 2016/0046961 A1

18 Feb 2016

US

14/685,504

13 Apr 2015

US 2016/0130609 A1

12 May 2016

US

14/685,513

13 Apr 2015

US 2016/0060653 A1

03 Mar 2016

US

14/685,514

13 Apr 2015

US 2016/0060654 A1

03 Mar 2016

US

14/685,516

13 Apr 2015

US 2016/0068864 A1

10 Mar 2016

US

15/090,511

04 Apr 2016

US 2017/0051312 A1

23 Feb 2017

US

15/343,156

03 Nov 2016

US

15/343,158

03 Nov 2016

US

15/435,233

16 Feb 2017

US 2017/0166893 A1

15 Jun 2017

US

15/803,424

03 Nov 2017

US 2018/0282764 A1

04 Oct 2018

US

15/915,020

07 Mar 2018

US 2019/0062790 A1

28 Feb 2019

US

15/925,544

19 Mar 2018

US 2018/0208931 A1

26 Jul 2018

US

15/947,680

06 Apr 2018

US 2018/0230495 A1

16 Aug 2018

US

15/947,700

06 Apr 2018

US 2018/0230496 A1

16 Aug 2018

US

15/947,718

06 Apr 2018

US 2018/0230497 A1

16 Aug 2018

US

15/959,715

23 Apr 2018

US 2018/0298406 A1

18 Oct 2018

US

15/959,735

23 Apr 2018

US 2018/0298407 A1

18 Oct 2018

US

15/959,762

23 Apr 2018

US 2018/0237801 A1

23 Aug 2018

US

15/959,782

23 Apr 2018

US 2018/0245100 A1

30 Aug 2018

US

15/959,802

23 Apr 2018

US 2018/0273981 A1

27 Sep 2018

US

15/965,598

27 Apr 2018

US 2018/0245101 A1

30 Aug 2018

US

15/965,603

27 Apr 2018

US 2018/0251791 A1

06 Sep 2018

US

15/981,807

16 May 2018

US 2018/0251793 A1

06 Sep 2018

US

15/981,808

16 May 2018

US 2018/0251794 A1

06 Sep 2018

US

15/981,809

16 May 2018

US 2018/0251795 A1

06 Sep 2018

US

16/033,002

11 Jul 2018

US 2018/0312874 A1

01 Nov 2018

US

16/033,005

11 Jul 2018

US 2018/0312875 A1

01 Nov 2018

US

16/033,016

11 Jul 2018

US 2018/0312876 A1

01 Nov 2018

US

16/136,159

19 Sep 2018

US 2019/0002921 A1

03 Jan 2019

US

16/136,165

19 Sep 2018

US 2019/0002922 A1

03 Jan 2019

US

16/136,168

19 Sep 2018

US 2019/0002923 A1

03 Jan 2019

US

16/136,175

19 Sep 2018

US 2019/0010520 A1

10 Jan 2019

US

16/201,836

27 Nov 2018

US 2019/0093129 A1

28 Mar 2019

US

16/201,848

27 Nov 2018

US 2019/0106711 A1

11 Apr 2019

US

16/201,853

27 Nov 2018

US 2019/0106712 A1

11 Apr 2019

US

16/201,855

27 Nov 2018

US 2019/0106713 A1

11 Apr 2019

US

16/201,862

27 Nov 2018

US 2019/0106714 A1

11 Apr 2019

US

16/201,865

27 Nov 2018

US 2019/0106715 A1

11 Apr 2019

US

16/276,343

14 Feb 2019

US

16/276,348

14 Feb 2019

US

16/276,352

14 Feb 2019

US

16/276,356

14 Feb 2019

US

16/276,361

14 Feb 2019

US

16/276,365

14 Feb 2019

US

16/276,368

14 Feb 2019

US

16/276,374

14 Feb 2019

US

16/277,090

15 Feb 2019

US

16/380,758

10 Apr 2019

US

16/380,781

10 Apr 2019

US

16/382,093

11 Apr 2019

US

16/382,096

11 Apr 2019

US

16/382,097

11 Apr 2019

US

16/382,100

11 Apr 2019

US

16/383,412

12 Apr 2019

US

16/383,422

12 Apr 2019

US

16/383,433

12 Apr 2019

US

16/383,443

12 Apr 2019

US

16/385,360

16 Apr 2019

US

16/385,383

16 Apr 2019

UZ

IAP20140559

15 Mar 2013

VN

1-2014-04335

15 Mar 2013

ZA

2017/00720

30 Jan 2017

REFERENCE / COUNTRY

SERIAL NUMBER / PUBLICATION NUMBER / PATENT NUMBER.

FILING DATE / PUBLICATION DATE /

ISSUE DATE

STATUS

SIG202.PRO

61/734,2

06-Dec-2012

Expired

SIG202.PRO2

61/758,624

30-Jan-2013

Expired

SIG202.PRO3

61/761,046

05-Feb-2013

Expired

SIG202.PRO4

61/794,422

15-Mar-2013

Expired

SIG202.PCT

PCT/US2013/073307

WO 2014/089290

5-Dec-2013

12-Jun-2014

Expired

SIG202.USCNT8

15/653,136

(Claims priority from ‘422 Provisional only)

18-Jul-2017

Pending

SIG202.USCNT1

15/188,911 (CON of ‘777)

US 2016-0298134 A1

21-Jun-2016

Pending

SIG202.USCNT2

15/188,924 (CON of ‘777)

US 2016-0298135 A1

21-Jun-2016

Pending

SIG202.USCNT3

15/188,927 (CON of ‘777)

US 2016-0298136 A1

21-Jun-2016

Pending

SIG202.USCNT4

15/188,931 (CON of ‘777)

US 2016-0298137 A1

21-Jun-2016

Pending

SIG202.USCNT7

15/456,204

US 2017-0191082 A1

10-Mar-2017

Pending

SIG202.EP

EP13859964.2

EP2928496

5-Dec-2013

Pending

SIG202.EPD3

EP16183723.2 EP3138910 (DIV of ‘964.2)

Validated in AT, BE, CZ, DK, EE, FI, FR, DE, IS, IE, IT, LT, LU, NL, NO,

PL, PT, SK, ES, SE, CH, TR, GB

5-Dec-2013

20-Sept-2017

Granted

SIG202.EPD4

EP16183724.0 EP3138911 (DIV of ‘964.2)

Validated in AT, BE, CZ, DK, EE, FI, FR, DE, IS, IE, IT, LT, LU, NL, NO,

PL, PT, SK, ES, SE, CH, TR, GB

5-Dec-2013

5-Dec-2018

Granted

SIG202.EPD5

EP16183725.7 EP3138912 (DIV of ‘964.2)

Validated in AT, BE, CZ, DK, EE, FI, FR, DE, IS, IE, IT, LT, LU, NL, NO,

PL, PT, SK, ES, SE, CH, TR, GB

5-Dec-2013

5-Dec-2018

Granted

SIG202.EPD6

EP18156734.8

EP3360964

14-Feb-2018

15-Aug-2018

Pending

Allowed – not yet granted

SIG202.EPD7

EP18160519.7

EP3363902

9-Mar-2018

22-Aug-2018

Pending

SIG202.AU

2013355214

5-Dec-2013

5-Jul-2018

Granted

SIG202.AU.DIV

2017204031

15-Jun-2017

27-Sept-2018

Granted

SIG202.AU.DIV2

2018229489

12-Sept-2018

Pending

Allowed – not yet grated

SIG202.BR

112015012375-9

5-Dec-2013

Pending

SIG202.CA

2,891,347

5-Dec-2013

27-Feb-2018

Granted

SIG202.CA.DIV

2,977,152

5-Dec-2013

9-Apr-2019

Granted

SIG202.CN

201380072477.4

105142669

ZL201380072477.4

5-Dec-2013

3-Jul-2018

Granted

SIG202.CN.DIV1

201810540449.5

108715602

30-May-2018

Pending

SIG202.CN.DIV2

201810574719.4

108913676

6-Jun-2019

Pending

SIG202.HK

16106396.9

1218389A

Based upon CN application

5-Dec-2013

17-2-2017

Pending

SIG202.IL

IL238856

5-Dec-2013

30-Jun-2018

Granted

SIG202.IL.DIV

IL257178

5-Dec-2013

Pending

SIG202.IN

1500KOLNP/2015

5-Dec-2013

Pending

SIG202.JP

2015-545838

5-Dec-2013

Pending

SIG202.JPDIV

2017-115672

13-Jun-2017

Pending

SIG202.JPDIV2

2018-183815

28-Sept-2018

Pending

SIG202.KR

10-2015-7013843

5-Dec-2013

26-Mar-2018

Granted

SIG202.KR.DIV

10-2018-7001934

5-Dec-2013

Pending

Allowed – not yet granted

SIG202.SG

11201503824S

5-Dec-2013

8-May-2018

Granted

SIG202.SG.DIV

10201800585V

5-Dec-2013

Pending

EXEMPLARY FAMILY SERIAL NO

PATENT TITLE

PCT/US2013/074611

CRISPR-CAS Component Systems, thods and Compositions for Sequence Manipulation

PCT/US2013/074743

CRISPR-CAS Systems and Methods for Altering Expressions of Gene Products

14/259,420

CRISPR-CAS Systems, Methods and Compositions For Sequence Manipulation in Eukaryotes

PCT/US2013/051418

Inducible DNA Binding Proteins and Genome Perturbation Tools and Applications Thereof

PCT/US2013/074825

Methods, Systems and Apparatus for Identifying Target Sequences for CAS Enzymes or CRISPR-CAS Systems for Target Sequences and Conveying Results Thereof

PCT/US2013/074812

Methods, Models, Systems and Apparatus for Identifying Target Sequences for CAS Enzymes or CRISPR-CAS Systems for Target Sequences and Conveying Results Thereof

PCT/US2013/074667

Delivery, Engineering and Optimization of Systems Methods and Compositions for Sequence Manipulation and Therapeutic Applications

PCT/US2014/041803

Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Applications

PCT/US2013/074691

Engineering and Optimization of Improved Systems, Methods and Enzyme Compositions for Sequence Manipulation

PCT/US2013/074736

Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation with Functional Domains

PCT/US2013/074819

Engineering of Systems, Methods and Optimized Guide Compositions for Sequence Manipulation

14/855,046

Recombinant Virus And Preparations Thereof

PCT/US2014/041800

Delivery, Engineering and Optimization of Tandem Guide Systems, Methods and Compositions for Sequence Manipulation

PCT/US2014/041806

Functional Genomics Using CRISPR-Cas Systems, Compositions, Methods, Screens and Applications Thereof

PCT/US2014/064663

CRISPR-Related Methods and Compositions with Governing gRNAS

PCT/US2014/069902

Compositions and Methods of Use of CRISPR-Cas Systems in Nucleotide Repeat Disorders

PCT/US2014/069897

Compositions and Methods of Use of CRISPR-CAS Systems in Nucleotide Repeat Disorders

15/171,141

CRISPR-CAS Systems, Crystal Structure and Uses Thereof

15/349,603

Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications

15/467,949

Use and Production of CHD8+/- Transgenic Animals with Behavioral Phenotypes Characteristic of Autism Spectrum Disorder

15/469,081

Functional Screening with Optimized Functional CRISPR-Cas Systems

PCT/US2015/067177

CRISPR Having or Associated with

Destabilization Domains

PCT/US2015/065385

Protected Guide RNAs (PGRNAs)

15/632,067

RNA-Targeting System

PCT/US2015/067138

Unbiased Identification of Double- Strand Breaks and Genomic Rearrangement by Genome-Wide Insert Capture Sequencing

PCT/US2015/065393

Dead Guides for CRISPR Transcription Factors

15/619,735

Escorted and Functionalized Guides for CRISPR-CAS Systems

15/619,737

Delivery, Use and Therapeutic Applications of CRISPR Systems and Compositions for Genome Editing as to Hematopoietic Stem Cells (HSCs)

15/640,103

CRISPR MEDIATED IN VIVO MODELING AND GENETIC SCREENING OF TUMOR GROWTH AND METASTASIS

PCT/US2016/038252

Engineering and Optimization of Systems, Methods, Enzymes and Guide Scaffolds of CAS9 Orthologs and Variants for Sequence Manipulation

PCT/US2016/038034

CRISPR Enzyme Mutations Reducing Off-Target Effects

PCT/US2016/038205

CRISPR Mediated Recording of Cellular Events

PCT/US2017/047458

Novel CRISPR Enzymes and Systems

PCT/US2017/053795

Systematic Screening and Mapping of Regulatory Elements in Non-Coding Genomic Regions, Methods, Compositions, and Applications Thereof

62/502,064

62/564,102

Methods for Identification and Modification of LNCRNA Associated with Target Genotypes and Phenotypes

62/529,573

Methods for Designing Guides Sequences for Guided Nucleases

PCT/US2014/070068

CRISPR-CAS Systems and Methods for Altering Expression of Gene Products, Structural Information and Inducible Modular CAS Enzymes

PCT/US2014/041804

DELIVERY AND USE OF THE CRISPR- CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC TARGETING AND THERAPY

PCT/US2014/070127

Delivery, Use and Therapeutic Applications of the CRISPR-Cas Systems and Compositions for Genomic Editing

PCT/US2014/041808

Delivery, Engineering and Optimization of Systems, Methods and Compositions for Targeting and Modeling Diseases and Disorders of Post Mitotic Cells

PCT/US2014/041809

Delivery, Use and therapeutic Applications of the CRISPR-Cas systems and Compositions for Targeting Disorders and Diseases Using Viral Components

PCT/US2014/070057

Delivery, Use and Therapeutic Applications of the CRISPR-CAS Systems and Compositions for Targeting Disorders and Diseases Using NanoParticle Components

PCT/US2013/074800

Functional Genomics Using CRISPR- CAS Systems, Compositions, Methods, Knock Out Libraries and Applications Thereof

PCT/US2014/070152

Engineering Of Systems, Methods And Optimized Guide Compositions with New Architectures For Sequence Manipulation

PCT/US2014/070175

Systems, Methods and Compositions for Sequence Manipulation with Optimized Functional CRISPR-CAS Systems

PCT/US2015/045504

Genome Editing Using CAS9 Nickases

15/467,888

Delivery, Use and Therapeutic Applications of the CRISPR-CAS Systems and Compositions for Modeling Competition of Multiple Cancer Mutations in Vivo