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Patents

Related

  • Limited use licenses


    Contents

    • ERS Genomics Limited patent rights (July 2019)
    • Sigma-Aldrich Co. LLC. Patent Rights (August 2019)
    • ​Broad Institute Patent Rights


    ERS Genomics Limited Patent Rights (July 2019)


    Granted Patents

    Country

    Application No.

    Filing Date

    Patent No.

    Grant Date

    AU

    2013266968

    15 Mar 2013

    AU 2013266968 B2

    07 Dec 2017

    CN

    201380038920.6

    15 Mar 2013

    CN 104854241 B

    14 Jul 2017

    EP

    13793997.1

    15 Mar 2013

    EP 2800811 B1

    10 May 2017

    EP

    17163434.8

    15 Mar 2013

    EP 3241902 B1

    28 Feb 2018

    EP

    18152360.6

    15 Mar 2013

    EP 3401400 B1

    03 Apr 2019

    GB

    1420270.9

    15 Mar 2013

    GB 2518764 C

    02 Mar 2016

    GB

    1601071.2

    15 Mar 2013

    GB 2537000 B

    08 Mar 2017

    HK

    15106335.4

    03 Jul 2015

    HK 1207107 B

    25 Aug 2017

    HK

    15112610.8

    23 Dec 2015

    HK 1211978 B

    04 May 2018

    HK

    17103002.1

    03 Jul 2015

    HK 1230233 B

    01 Jun 2018

    JP

    20150514015

    15 Mar 2013

    JP 6343605 B

    25 May 2018

    MX

    20140014477

    15 Mar 2013

    MX 349744 B

    10 Aug 2017

    NZ

    714353

    15 Mar 2013

    NZ 714353 B2

    29 Aug 2017

    SG

    11201407702

    15 Mar 2013

    SG 11201407702X

    20 Mar 2017

    SG

    10201701800Y

    15 Mar 2013

    SG 10201701800Y

    21 Nov 2018

    TN

    2014/0493

    25 Nov 2014

    TN 24223

    03 Jun 2016

    UA

    A201413835

    15 Mar 2013

    UA 118014

    12 Nov 2018

    US

    13/842,859

    15 Mar 2013

    US 10266850 B2

    23 Apr 2019

    US

    14/685,502

    13 Apr 2015

    US 10000772 B2

    19 Jun 2018

    US

    14/942,782

    16 Nov 2015

    US 10227611 B2

    12 Mar 2019

    US

    15/138,604

    26 Apr 2016

    US 10113167 B2

    30 Oct 2018

    ZA

    2014/07881

    29 Oct 2014

    ZA 2014/07881

    31 Jan 2018

    DE

    2020132012240.4

    15 Mar 2013

    DE 202013012240 U1

    02 Feb 2016

    DE

    2020132012241.2

    15 Mar 2013

    DE 202013012241 U1

    18 Jan 2016

    DE

    2020132012242.0

    15 Mar 2013

    DE 202013012242 U1

    02 Feb 2016






    Patent Applications

    Country

    Application No.

    Filing Date

    Publication No.

    Publication Date

    PCT

    PCT/US2013/032589

    15 Mar 2013

    WO 2013/176772 A1

    28 Nov 2013

    AE

    P1296/2014

    25 Nov 2014



    AU

    2017225060

    07 Sep 2017

    AU 2017225060 A1

    28 Sep 2017

    AU

    2019201850

    18 Mar 2019



    BR

    1120140294410

    15 Mar 2013

    BR 1120140294410 A2

    27 Jun 2017

    CA

    2872241

    15 Mar 2013

    CA 2872241 A1

    28 Nov 2013

    CL

    2014003208

    25 Nov 2014

    CL 2014003208 A1

    19 Jun 2015

    CN

    201710585690.5

    15 Mar 2013

    CN 107603976 A

    19 Jan 2018

    CO

    20140259531

    25 Nov 2014

    CO 7151523 A2

    29 Dec 2014

    CR

    20140538

    24 Nov 2014

    CR 20140538 A

    18 Feb 2015

    DZ

    140780

    22 Dec 2014



    EA

    201401319

    15 Mar 2013

    EA 201401319 A1

    29 May 2015

    EC

    IEPI-2014-28704

    15 Mar 2013


    30 Oct 2015

    EG

    PCT1887/2014

    15 Mar 2013



    EP

    19157590.1

    15 Mar 2013



    GB

    1511669.2

    15 Mar 2013

    GB 201511669 D0

    19 Aug 2015

    GE

    AP2013013674

    15 Mar 2013



    HK

    15104473.1

    12 May 2015

    HK 1204003 A1

    06 Nov 2015

    HK

    19119875.3

    22 Feb 2019



    ID

    P00201407783

    10 Dec 2014

    2016/03367

    13 May 2016

    IL

    235461

    15 Mar 2013


    31 Dec 2014

    IL

    261563

    15 Mar 2013


    31 Oct 2018

    IL

    261565

    15 Mar 2013


    31 Oct 2018

    IL

    261566

    15 Mar 2013


    31 Oct 2018

    IL

    261567

    15 Mar 2013


    31 Oct 2018

    IL

    261568

    15 Mar 2013


    31 Oct 2018

    IL

    261569

    15 Mar 2013


    31 Oct 2018

    IL

    261570

    15 Mar 2013


    31 Oct 2018

    IN

    2995/KOLNP/2014

    15 Mar 2013

    2995/KOLNP/2014 A

    04 Dec 2015

    JP

    2018-097369

    21 May 2018

    2018-138054

    06 Sep 2018

    KE

    P/2014/002178

    25 Nov 2014



    KR

    1020147036096

    15 Mar 2013

    KR 1020150016588 A

    12 Feb 2015

    KR

    1020177034069

    15 Mar 2013

    KR 1020170134766 A

    06 Dec 2017

    KS

    P/2017/000022

    15 Mar 2013



    LY

    4958/2014

    15 Mar 2013



    MA

    37663

    15 Mar 2013

    MA 37663 A1

    31 May 2017

    MX

    2017010309

    15 Mar 2013



    MX

    2019001995

    15 Mar 2013



    MY

    PI2014003102

    15 Mar 2013



    MY

    PI2018700285

    15 Mar 2013



    NZ

    701326

    15 Mar 2013



    NZ

    728024

    15 Mar 2013

    NZ 728024 A

    27 Jan 2017

    NZ

    730667

    15 Mar 2013

    NZ 730667 A1

    31 Mar 2017

    OM

    P/2014/00268

    25 Nov 2014



    PA

    90441-01

    25 Nov 2014


    12 Sep 2016

    PE

    002211-2014/DIN

    15 Mar 2013

    PE 03362015 A1

    25 Mar 2015

    PH

    12014502574

    19 Nov 2014

    PH 12014502574 A1

    21 Jan 2015

    QA

    20141100400

    15 Mar 2013



    SG

    10201809817U

    15 Mar 2013

    SG 10201809817U A

    28 Dec 2018

    SY

    2014120156

    15 Mar 2013



    TH

    1401007063

    15 Mar 2013

    TH 173084

    15 Feb 2018

    UA

    A201808549

    07 Aug 2018



    US

    61/652,086

    25 May 2012



    US

    61/716,256

    19 Oct 2012



    US

    61/757,640

    28 Jan 2013



    US

    61/765,576

    15 Feb 2013



    US

    14/403,475

    24 Nov 2014

    US 2016/0046961 A1

    18 Feb 2016

    US

    14/685,504

    13 Apr 2015

    US 2016/0130609 A1

    12 May 2016

    US

    14/685,513

    13 Apr 2015

    US 2016/0060653 A1

    03 Mar 2016

    US

    14/685,514

    13 Apr 2015

    US 2016/0060654 A1

    03 Mar 2016

    US

    14/685,516

    13 Apr 2015

    US 2016/0068864 A1

    10 Mar 2016

    US

    15/090,511

    04 Apr 2016

    US 2017/0051312 A1

    23 Feb 2017

    US

    15/343,156

    03 Nov 2016



    US

    15/343,158

    03 Nov 2016



    US

    15/435,233

    16 Feb 2017

    US 2017/0166893 A1

    15 Jun 2017

    US

    15/803,424

    03 Nov 2017

    US 2018/0282764 A1

    04 Oct 2018

    US

    15/915,020

    07 Mar 2018

    US 2019/0062790 A1

    28 Feb 2019

    US

    15/925,544

    19 Mar 2018

    US 2018/0208931 A1

    26 Jul 2018

    US

    15/947,680

    06 Apr 2018

    US 2018/0230495 A1

    16 Aug 2018

    US

    15/947,700

    06 Apr 2018

    US 2018/0230496 A1

    16 Aug 2018

    US

    15/947,718

    06 Apr 2018

    US 2018/0230497 A1

    16 Aug 2018

    US

    15/959,715

    23 Apr 2018

    US 2018/0298406 A1

    18 Oct 2018

    US

    15/959,735

    23 Apr 2018

    US 2018/0298407 A1

    18 Oct 2018

    US

    15/959,762

    23 Apr 2018

    US 2018/0237801 A1

    23 Aug 2018

    US

    15/959,782

    23 Apr 2018

    US 2018/0245100 A1

    30 Aug 2018

    US

    15/959,802

    23 Apr 2018

    US 2018/0273981 A1

    27 Sep 2018

    US

    15/965,598

    27 Apr 2018

    US 2018/0245101 A1

    30 Aug 2018

    US

    15/965,603

    27 Apr 2018

    US 2018/0251791 A1

    06 Sep 2018

    US

    15/981,807

    16 May 2018

    US 2018/0251793 A1

    06 Sep 2018

    US

    15/981,808

    16 May 2018

    US 2018/0251794 A1

    06 Sep 2018

    US

    15/981,809

    16 May 2018

    US 2018/0251795 A1

    06 Sep 2018

    US

    16/033,002

    11 Jul 2018

    US 2018/0312874 A1

    01 Nov 2018

    US

    16/033,005

    11 Jul 2018

    US 2018/0312875 A1

    01 Nov 2018

    US

    16/033,016

    11 Jul 2018

    US 2018/0312876 A1

    01 Nov 2018

    US

    16/136,159

    19 Sep 2018

    US 2019/0002921 A1

    03 Jan 2019

    US

    16/136,165

    19 Sep 2018

    US 2019/0002922 A1

    03 Jan 2019

    US

    16/136,168

    19 Sep 2018

    US 2019/0002923 A1

    03 Jan 2019

    US

    16/136,175

    19 Sep 2018

    US 2019/0010520 A1

    10 Jan 2019

    US

    16/201,836

    27 Nov 2018

    US 2019/0093129 A1

    28 Mar 2019

    US

    16/201,848

    27 Nov 2018

    US 2019/0106711 A1

    11 Apr 2019

    US

    16/201,853

    27 Nov 2018

    US 2019/0106712 A1

    11 Apr 2019

    US

    16/201,855

    27 Nov 2018

    US 2019/0106713 A1

    11 Apr 2019

    US

    16/201,862

    27 Nov 2018

    US 2019/0106714 A1

    11 Apr 2019

    US

    16/201,865

    27 Nov 2018

    US 2019/0106715 A1

    11 Apr 2019

    US

    16/276,343

    14 Feb 2019



    US

    16/276,348

    14 Feb 2019



    US

    16/276,352

    14 Feb 2019



    US

    16/276,356

    14 Feb 2019



    US

    16/276,361

    14 Feb 2019



    US

    16/276,365

    14 Feb 2019



    US

    16/276,368

    14 Feb 2019



    US

    16/276,374

    14 Feb 2019



    US

    16/277,090

    15 Feb 2019



    US

    16/380,758

    10 Apr 2019



    US

    16/380,781

    10 Apr 2019



    US

    16/382,093

    11 Apr 2019



    US

    16/382,096

    11 Apr 2019



    US

    16/382,097

    11 Apr 2019



    US

    16/382,100

    11 Apr 2019



    US

    16/383,412

    12 Apr 2019



    US

    16/383,422

    12 Apr 2019



    US

    16/383,433

    12 Apr 2019



    US

    16/383,443

    12 Apr 2019



    US

    16/385,360

    16 Apr 2019



    US

    16/385,383

    16 Apr 2019



    UZ

    IAP20140559

    15 Mar 2013



    VN

    1-2014-04335

    15 Mar 2013



    ZA

    2017/00720

    30 Jan 2017




    Sigma-Aldrich Co. LLC. Patent Rights (August 2019):


    REFERENCE / COUNTRY

    SERIAL NUMBER / PUBLICATION NUMBER / PATENT NUMBER.

    FILING DATE / PUBLICATION DATE /

    ISSUE DATE

    STATUS

    SIG202.PRO

    61/734,2

    06-Dec-2012

    Expired

    SIG202.PRO2

    61/758,624

    30-Jan-2013

    Expired

    SIG202.PRO3

    61/761,046

    05-Feb-2013

    Expired

    SIG202.PRO4

    61/794,422

    15-Mar-2013

    Expired

    SIG202.PCT

    PCT/US2013/073307


    WO 2014/089290

    5-Dec-2013


    12-Jun-2014

    Expired

    SIG202.USCNT8

    15/653,136


    (Claims priority from ‘422 Provisional only)

    18-Jul-2017

    Pending

    SIG202.USCNT1

    15/188,911 (CON of ‘777)

    US 2016-0298134 A1

    21-Jun-2016

    Pending

    SIG202.USCNT2

    15/188,924 (CON of ‘777)

    US 2016-0298135 A1

    21-Jun-2016

    Pending

    SIG202.USCNT3

    15/188,927 (CON of ‘777)

    US 2016-0298136 A1

    21-Jun-2016

    Pending

    SIG202.USCNT4

    15/188,931 (CON of ‘777)

    US 2016-0298137 A1

    21-Jun-2016

    Pending

    SIG202.USCNT7

    15/456,204


    US 2017-0191082 A1

    10-Mar-2017

    Pending

    SIG202.EP

    EP13859964.2


    EP2928496

    5-Dec-2013

    Pending

    SIG202.EPD3

    EP16183723.2 EP3138910 (DIV of ‘964.2)

    Validated in AT, BE, CZ, DK, EE, FI, FR, DE, IS, IE, IT, LT, LU, NL, NO,

    PL, PT, SK, ES, SE, CH, TR, GB

    5-Dec-2013


    20-Sept-2017

    Granted

    SIG202.EPD4

    EP16183724.0 EP3138911 (DIV of ‘964.2)

    Validated in AT, BE, CZ, DK, EE, FI, FR, DE, IS, IE, IT, LT, LU, NL, NO,

    PL, PT, SK, ES, SE, CH, TR, GB

    5-Dec-2013


    5-Dec-2018

    Granted

    SIG202.EPD5

    EP16183725.7 EP3138912 (DIV of ‘964.2)

    Validated in AT, BE, CZ, DK, EE, FI, FR, DE, IS, IE, IT, LT, LU, NL, NO,

    PL, PT, SK, ES, SE, CH, TR, GB

    5-Dec-2013


    5-Dec-2018

    Granted

    SIG202.EPD6

    EP18156734.8


    EP3360964

    14-Feb-2018


    15-Aug-2018

    Pending


    Allowed – not yet granted

    SIG202.EPD7

    EP18160519.7


    EP3363902

    9-Mar-2018


    22-Aug-2018

    Pending

    SIG202.AU

    2013355214

    5-Dec-2013


    5-Jul-2018

    Granted

    SIG202.AU.DIV

    2017204031

    15-Jun-2017


    27-Sept-2018

    Granted

    SIG202.AU.DIV2

    2018229489

    12-Sept-2018

    Pending


    Allowed – not yet grated

    SIG202.BR

    112015012375-9

    5-Dec-2013

    Pending

    SIG202.CA

    2,891,347

    5-Dec-2013


    27-Feb-2018

    Granted

    SIG202.CA.DIV

    2,977,152

    5-Dec-2013


    9-Apr-2019

    Granted

    SIG202.CN

    201380072477.4


    105142669


    ZL201380072477.4

    5-Dec-2013




    3-Jul-2018

    Granted

    SIG202.CN.DIV1

    201810540449.5


    108715602

    30-May-2018

    Pending

    SIG202.CN.DIV2

    201810574719.4


    108913676

    6-Jun-2019

    Pending

    SIG202.HK

    16106396.9


    1218389A


    Based upon CN application

    5-Dec-2013


    17-2-2017

    Pending

    SIG202.IL

    IL238856

    5-Dec-2013


    30-Jun-2018

    Granted

    SIG202.IL.DIV

    IL257178

    5-Dec-2013

    Pending

    SIG202.IN

    1500KOLNP/2015

    5-Dec-2013

    Pending

    SIG202.JP

    2015-545838

    5-Dec-2013

    Pending

    SIG202.JPDIV

    2017-115672

    13-Jun-2017

    Pending

    SIG202.JPDIV2

    2018-183815

    28-Sept-2018

    Pending

    SIG202.KR

    10-2015-7013843

    5-Dec-2013


    26-Mar-2018

    Granted

    SIG202.KR.DIV

    10-2018-7001934

    5-Dec-2013

    Pending


    Allowed – not yet granted

    SIG202.SG

    11201503824S

    5-Dec-2013


    8-May-2018

    Granted

    SIG202.SG.DIV

    10201800585V

    5-Dec-2013

    Pending


    Broad Institute Patent Rights

    EXEMPLARY FAMILY SERIAL NO

    PATENT TITLE

    PCT/US2013/074611

    CRISPR-CAS Component Systems, thods and Compositions for Sequence Manipulation

    PCT/US2013/074743

    CRISPR-CAS Systems and Methods for Altering Expressions of Gene Products

    14/259,420

    CRISPR-CAS Systems, Methods and Compositions For Sequence Manipulation in Eukaryotes

    PCT/US2013/051418

    Inducible DNA Binding Proteins and Genome Perturbation Tools and Applications Thereof

    PCT/US2013/074825

    Methods, Systems and Apparatus for Identifying Target Sequences for CAS Enzymes or CRISPR-CAS Systems for Target Sequences and Conveying Results Thereof

    PCT/US2013/074812

    Methods, Models, Systems and Apparatus for Identifying Target Sequences for CAS Enzymes or CRISPR-CAS Systems for Target Sequences and Conveying Results Thereof

    PCT/US2013/074667

    Delivery, Engineering and Optimization of Systems Methods and Compositions for Sequence Manipulation and Therapeutic Applications

    PCT/US2014/041803

    Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Applications

    PCT/US2013/074691

    Engineering and Optimization of Improved Systems, Methods and Enzyme Compositions for Sequence Manipulation

    PCT/US2013/074736

    Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation with Functional Domains

    PCT/US2013/074819

    Engineering of Systems, Methods and Optimized Guide Compositions for Sequence Manipulation

    14/855,046

    Recombinant Virus And Preparations Thereof

    PCT/US2014/041800

    Delivery, Engineering and Optimization of Tandem Guide Systems, Methods and Compositions for Sequence Manipulation

    PCT/US2014/041806

    Functional Genomics Using CRISPR-Cas Systems, Compositions, Methods, Screens and Applications Thereof

    PCT/US2014/064663

    CRISPR-Related Methods and Compositions with Governing gRNAS

    PCT/US2014/069902

    Compositions and Methods of Use of CRISPR-Cas Systems in Nucleotide Repeat Disorders

    PCT/US2014/069897

    Compositions and Methods of Use of CRISPR-CAS Systems in Nucleotide Repeat Disorders

    15/171,141

    CRISPR-CAS Systems, Crystal Structure and Uses Thereof

    15/349,603

    Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications

    15/467,949

    Use and Production of CHD8+/- Transgenic Animals with Behavioral Phenotypes Characteristic of Autism Spectrum Disorder

    15/469,081

    Functional Screening with Optimized Functional CRISPR-Cas Systems

    PCT/US2015/067177

    CRISPR Having or Associated with

    Destabilization Domains

    PCT/US2015/065385

    Protected Guide RNAs (PGRNAs)

    15/632,067

    RNA-Targeting System

    PCT/US2015/067138

    Unbiased Identification of Double- Strand Breaks and Genomic Rearrangement by Genome-Wide Insert Capture Sequencing

    PCT/US2015/065393

    Dead Guides for CRISPR Transcription Factors

    15/619,735

    Escorted and Functionalized Guides for CRISPR-CAS Systems

    15/619,737

    Delivery, Use and Therapeutic Applications of CRISPR Systems and Compositions for Genome Editing as to Hematopoietic Stem Cells (HSCs)

    15/640,103

    CRISPR MEDIATED IN VIVO MODELING AND GENETIC SCREENING OF TUMOR GROWTH AND METASTASIS

    PCT/US2016/038252

    Engineering and Optimization of Systems, Methods, Enzymes and Guide Scaffolds of CAS9 Orthologs and Variants for Sequence Manipulation

    PCT/US2016/038034

    CRISPR Enzyme Mutations Reducing Off-Target Effects

    PCT/US2016/038205

    CRISPR Mediated Recording of Cellular Events

    PCT/US2017/047458

    Novel CRISPR Enzymes and Systems

    PCT/US2017/053795

    Systematic Screening and Mapping of Regulatory Elements in Non-Coding Genomic Regions, Methods, Compositions, and Applications Thereof

    62/502,064

    62/564,102

    Methods for Identification and Modification of LNCRNA Associated with Target Genotypes and Phenotypes

    62/529,573

    Methods for Designing Guides Sequences for Guided Nucleases

    PCT/US2014/070068

    CRISPR-CAS Systems and Methods for Altering Expression of Gene Products, Structural Information and Inducible Modular CAS Enzymes

    PCT/US2014/041804

    DELIVERY AND USE OF THE CRISPR- CAS SYSTEMS, VECTORS AND COMPOSITIONS FOR HEPATIC TARGETING AND THERAPY

    PCT/US2014/070127

    Delivery, Use and Therapeutic Applications of the CRISPR-Cas Systems and Compositions for Genomic Editing

    PCT/US2014/041808

    Delivery, Engineering and Optimization of Systems, Methods and Compositions for Targeting and Modeling Diseases and Disorders of Post Mitotic Cells

    PCT/US2014/041809

    Delivery, Use and therapeutic Applications of the CRISPR-Cas systems and Compositions for Targeting Disorders and Diseases Using Viral Components

    PCT/US2014/070057

    Delivery, Use and Therapeutic Applications of the CRISPR-CAS Systems and Compositions for Targeting Disorders and Diseases Using NanoParticle Components

    PCT/US2013/074800

    Functional Genomics Using CRISPR- CAS Systems, Compositions, Methods, Knock Out Libraries and Applications Thereof

    PCT/US2014/070152

    Engineering Of Systems, Methods And Optimized Guide Compositions with New Architectures For Sequence Manipulation

    PCT/US2014/070175

    Systems, Methods and Compositions for Sequence Manipulation with Optimized Functional CRISPR-CAS Systems

    PCT/US2015/045504

    Genome Editing Using CAS9 Nickases

    15/467,888

    Delivery, Use and Therapeutic Applications of the CRISPR-CAS Systems and Compositions for Modeling Competition of Multiple Cancer Mutations in Vivo

    ​










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