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Products associated with key targets involved in coronavirus research

Related

  • Information and products associated with novel coronavirus research
    • SimpleStep ELISA® technology: accuracy and speed when assessing COVID-19
      • Abcam scientists’ top tips for resuming research post-COVID-19
        • ​Immunology and infectious disease hub


          Overview

          • Products to support coronavirus research
          • Products specific for ACE2
          • Products specific for TMPRSS2
          • Products specific for DPP4
          • Products targeting other key host targets
            • Targets involved in prognostic factors
            • Investigational therapeutic targets
            • Targets involved in virus recognition 


          Products to support coronavirus research

          Coronavirus infection is dependent on the effective binding of viral proteins to cellular receptors. For example, Angiotensin-converting enzyme 2 (ACE2) and Dipeptidyl peptidase-4 (DPP4) have been identified as receptors for entry into the host cell used by SARS-Cov-2 and MERS-Cov, respectively. Upon infection and viral recognition, an immune response is triggered. Here, you can find information on featured products involved in coronavirus infection, recognition, and targeted immune response.  

          Abcam offers a variety of tools used to help understand and accelerate infectious disease research, including SARS-CoV-2. Our product range for SARS-CoV-2 products can be found here.

          If there is a product you need for COVID-19-related research that is not listed here, please contact us and we may be able to help. 


          Products specific for ACE2

          Featured antibodies and ELISA kits

          Product nameabIDImageApplication Species
          Recombinant Anti-ACE2 antibody [EPR4435(2)] ab108252​ELISA, WB, IP, IHC-PMouse, Rat, Human
          Anti-ACE2 antibodyab15348WB, IHC-PMouse, Rat, Human
          Human ACE2 ELISA Kit ab235649​Sandwich (quantitative)Human

          Recombinant Anti-ACE2 antibody [EPR24705-45]

          ab272500​Flow Cyt, IP, WB, ICC, IHC-PHuman

          See a complete list of antibodies targeting ACE2. 

          See a complete list of ELISA Kits and antibody pairs targeting ACE2. 

          Featured proteins 

          Product name abID
          Recombinant Human ACE2 protein ab151852 
          Recombinant Human ACE2 protein (Fc Chimera) ab273687 
          Recombinant Human ACE2 (mutated H374N + H378N) protein (Fc Chimera) ab273885 
          DX600 ACE2 inhibitor ab273525 

          See a complete list of proteins targeting ACE2. 

          Featured cell lines and lysates

          Product nameabID
          Human ACE2 knockout HepG2 cell line ab273733 
          Human ACE2 knockout HepG2 cell lysate ab275495 
          Human ACE2 knockout Caco-2 cell line ab273731 
          Human ACE2 knockout Caco-2 cell lysate  ab275516 

          See a complete list of cell lines and lysates targeting ACE2. 

          Products specific for TMPRSS2

          Featured products

          Product nameabIDImageApplicationSpecies 
          Anti-TMPRSS2 antibody [EPR24407-87]  ab280567 Flow Cyt, IP, ICCHuman
          Recombinant Anti-TMPRSS2 antibody [EPR3862] ab109131