Copper bis-3,5-diisopropylsalicylate, Protein kinase C inhibitor (ab142270)

Overview

  • Product name

    Copper bis-3,5-diisopropylsalicylate, Protein kinase C inhibitor
  • Description

    Protein kinase C inhibitor
  • Biological description

    Protein kinase C inhibitor. Reduces the activity of TPA stimulated protein kinase C in vitro and in vivo. Has anti-tumour effects in vitro and anti-ROS activity in vivo.
  • Purity

    > 98%
  • CAS Number

    21246-18-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Bis[2-hydroxy-3,5-bis(1-methylethyl)benzoato-O1,O2]-copper(II)
  • Molecular weight

    506.11
  • Molecular formula

    C26H34CuO6
  • PubChem identifier

    54689798
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)C1=CC(=C(C(=C1)C(=O)O)[O-])C(C)C.CC(C)C1=CC(=C(C(=C1)C(=O)O)[O-])C(C)C.[Cu+2]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Durán HA  et al. Inhibition of benzoyl peroxide-induced tumor promotion and progression by copper(II)(3,5-diisopropylsalicylate)2. Cancer Lett 69:167-72 (1993). Read more (PubMed: 8513442) »
  • Keshavarzian A  et al. Agents capable of eliminating reactive oxygen species. Catalase, WR-2721, or Cu(II)2(3,5-DIPS)4 decrease experimental colitis. Dig Dis Sci 37:1866-73 (1992). Read more (PubMed: 1335406) »
  • Nilsson K Effects of Cu(II) (3,5-diisopropylsalicylate)2 on soluble protein kinase C activity in rat liver. Cancer Lett 47:169-77 (1989). Read more (PubMed: 2635641) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab142270.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up