Overview

  • Product name

    Cordycepin (3-deoxyadenosine), Nucleoside antagonist
  • Description

    Nucleoside antagonist. Inhibits NF-κB signaling
  • Alternative names

    • 3'-deoxyadenosine
  • Biological description

    Nucleoside antagonist, able to interfere with RNA synthesis. Inhibits NF-κB signaling. Anti-inflammatory and antitumor effects in vitro and in vivo.
  • Purity

    > 98%
  • CAS Number

    73-03-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Seo MJ  et al. Effect of cordycepin on the expression of the inflammatory cytokines TNF-alpha, IL-6, and IL-17A in C57BL/6 mice. J Microbiol Biotechnol 23:156-60 (2013). Read more (PubMed: 23412056) »
  • Yao LH  et al. Cordycepin suppresses excitatory synaptic transmission in rat hippocampal slices via a presynaptic mechanism. CNS Neurosci Ther 19:216-21 (2013). Read more (PubMed: 23419191) »
  • Lee HJ  et al. The nucleoside antagonist cordycepin causes DNA double strand breaks in breast cancer cells. Invest New Drugs 30:1917-25 (2012). Read more (PubMed: 22821173) »
  • Ren Z  et al. Cordycepin suppresses TNF-a-induced NF-?B activation by reducing p65 transcriptional activity, inhibiting I?Ba phosphorylation, and blocking IKK? ubiquitination. Int Immunopharmacol 14:698-703 (2012). Read more (PubMed: 23102662) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141500.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up