Key features and details
- Rabbit polyclonal to Corin
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
Product nameAnti-Corin antibody
See all Corin primary antibodies
DescriptionRabbit polyclonal to Corin
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Rat
Predicted to work with: Mouse, Human
- Rat cardiac muscle tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 1% BSA, 50% Glycerol
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab209963 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
FunctionSerine-type endopeptidase involved in atrial natriuretic peptide hormone processing. Converts through proteolytic cleavage the non-functional propeptide NPPA/ANP into the active hormone which promotes natriuresis, diuresis, and vasodilatation. May also process pro-NPPB the B-type natriuretic peptide.
Tissue specificityHighly expressed in heart. Expressed in heart myocytes.
Sequence similaritiesBelongs to the peptidase S1 family.
Contains 2 FZ (frizzled) domains.
Contains 7 LDL-receptor class A domains.
Contains 1 peptidase S1 domain.
Contains 1 SRCR domain.
modificationsN-glycosylated; required for processing and activation.
Activated through proteolytic processing by a trypsin-like protease; cleaved into a N-terminal propeptide and an activated corin protease fragment.
A disulfide bond links the N-terminal propeptide and the activated corin protease fragment.
Cellular localizationCell membrane.
- Information by UniProt
- activated protease fragment antibody
- ATC 2 antibody
- ATC2 antibody
ab209963 has not yet been referenced specifically in any publications.