Overview

  • Product name

    Corticosterone, endogenous steroid hormone
  • Description

    Potent endogenous glucocorticoid and mineralocorticoid receptor agonist
  • Biological description

    Potent endogenous glucocorticoid and mineralocorticoid receptor agonist (EC50 = 20 nM, GR). Induces apoptosis. Modulates carbohydrate, potassium, and sodium metabolism in vivo. Blood-brain barrier permeable.
  • Purity

    > 96%
  • CAS Number

    50-22-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Mora F  et al. Stress, neurotransmitters, corticosterone and body-brain integration. Brain Res 1476:71-85 (2012). Read more (PubMed: 22285436) »
  • Schoffelmeer AN  et al. Glucocorticoid receptor activation potentiates the morphine-induced adaptive increase in dopamine D-1 receptor efficacy in gamma-aminobutyric acid neurons of rat striatum/nucleus accumbens. J Pharmacol Exp Ther 274:1154-60 (1995). Read more (PubMed: 7562482) »
  • Ronken E  et al. Glucocorticoid and mineralocorticoid receptors differentially modulate cultured dopaminergic neurons of rat ventral mesencephalon. Eur J Pharmacol 263:149-56 (1994). Read more (PubMed: 7821346) »
See all 2 Publications for this product

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