Key features and details
- Rabbit polyclonal to Cortisol Binding Globulin
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Cortisol Binding Globulin antibody
See all Cortisol Binding Globulin primary antibodies
DescriptionRabbit polyclonal to Cortisol Binding Globulin
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Recombinant protein fragment corresponding to a region within amino acids 105 and 353 of Human Cortisol Binding Globulin (NP_001747)
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96270 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 45 kDa.|
|ICC/IF||1/100 - 1/200.|
FunctionMajor transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Tissue specificityPlasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells.
Involvement in diseaseDefects in SERPINA6 are a cause of corticosteroid-binding globulin deficiency (CBG deficiency) [MIM:611489]. CBG deficiency is an extremely rare hereditary disorder characterized by reduced corticosteroid-binding capacity with normal or low plasma corticosteroid-binding globulin concentration, and normal or low basal cortisol levels associated with hypo/hypertension and muscle fatigue.
Sequence similaritiesBelongs to the serpin family.
modificationsN-glycosylated; binds 5 oligosaccharide chains.
Glycosylation in position Asn-260 is needed for steroid binding.
- Information by UniProt
- CBG antibody
- CBG_HUMAN antibody
- corticosteroid binding globulin antibody
ab96270 has not yet been referenced specifically in any publications.