Anti-COTL1 antibody (ab215064)
Key features and details
- Sheep polyclonal to COTL1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-COTL1 antibody
See all COTL1 primary antibodies -
Description
Sheep polyclonal to COTL1 -
Host species
Sheep -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow -
Immunogen
Recombinant full length protein corresponding to Human COTL1 aa 1 to the C-terminus. (Derived from E.coli).
Database link: Q14019 -
Positive control
- Human placenta tissue lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: 100% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
The IgG fraction of immunized serum was purified by antigen affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab215064 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000 - 1/2000. Detects a band of approximately 15 kDa (predicted molecular weight: 16 kDa).
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Notes |
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WB
1/1000 - 1/2000. Detects a band of approximately 15 kDa (predicted molecular weight: 16 kDa). |
Target
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Function
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. -
Tissue specificity
Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas. -
Sequence similarities
Belongs to the actin-binding proteins ADF family. Coactosin subfamily.
Contains 1 ADF-H domain. -
Cellular localization
Cytoplasm > cytoskeleton. - Information by UniProt
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Database links
- Entrez Gene: 617165 Cow
- Entrez Gene: 23406 Human
- Entrez Gene: 72042 Mouse
- Entrez Gene: 361422 Rat
- Omim: 606748 Human
- SwissProt: Q2HJ57 Cow
- SwissProt: Q14019 Human
- SwissProt: Q9CQI6 Mouse
see all -
Alternative names
- CLP antibody
- Coactosin like 1 antibody
- Coactosin-like protein antibody
see all
Images
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Anti-COTL1 antibody (ab215064) at 1/1000 dilution + Human placenta tissue lysate
Predicted band size: 16 kDa
Observed band size: 15 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (0)
ab215064 has not yet been referenced specifically in any publications.