Anti-COX IV antibody [mAbcam33985] - Mitochondrial Marker (ab33985)

Mouse monoclonal COX IV antibody [mAbcam33985]. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Sheep, Cow, Human, Xenopus laevis, Monkey, African green monkey and more.

Publishing research using ab33985? Please let us know so that we can cite the reference in this datasheet.

ab33985 has been referenced in 48 publications.

  • Gao Y  et al. Mitochondrial metabolism is inhibited by the HIF1a-MYC-PGC-1ß axis in BRAF V600E thyroid cancer. FEBS J 286:1420-1436 (2019). PubMed: 30768848
  • Irías-Mata A  et al. a-Tocopherol transfer protein does not regulate the cellular uptake and intracellular distribution of a- and ?-tocopherols and -tocotrienols in cultured liver cells. Redox Biol 19:28-36 (2018). PubMed: 30098456
  • Li XQ  et al. Inhibiting aberrant p53-PUMA feedback loop activation attenuates ischaemia reperfusion-induced neuroapoptosis and neuroinflammation in rats by downregulating caspase 3 and the NF-?B cytokine pathway. J Neuroinflammation 15:250 (2018). PubMed: 30172256
  • Keller G  et al. Mitochondrial dysfunction in preclinical genetic prion disease: A target for preventive treatment? Neurobiol Dis 124:57-66 (2018). PubMed: 30423473
  • Kim MJ  et al. Delivery of exogenous mitochondria via centrifugation enhances cellular metabolic function. Sci Rep 8:3330 (2018). PubMed: 29463809
  • Pareek G  et al. Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration. Cell Death Dis 9:304 (2018). PubMed: 29467464
  • Lloyd-Lewis B  et al. Stat3-mediated alterations in lysosomal membrane protein composition. J Biol Chem 293:4244-4261 (2018). PubMed: 29343516
  • Sinha S  et al. A double helical motif in OCIAD2 is essential for its localization, interactions and STAT3 activation. Sci Rep 8:7362 (2018). PubMed: 29743632
  • Samdal H  et al. Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells. FEBS J 285:2446-2467 (2018). PubMed: 29723445
  • Qu C  et al. Dihydroartemisinin Exerts Anti-Tumor Activity by Inducing Mitochondrion and Endoplasmic Reticulum Apoptosis and Autophagic Cell Death in Human Glioblastoma Cells. Front Cell Neurosci 11:310 (2017). WB ; Human . PubMed: 29033794
  • Yan Z  et al. Exercise leads to unfavourable cardiac remodelling and enhanced metabolic homeostasis in obese mice with cardiac and skeletal muscle autophagy deficiency. Sci Rep 7:7894 (2017). WB ; Mouse . PubMed: 28801668
  • Le NH  et al. Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle. J Inflamm (Lond) 14:9 (2017). WB ; Mouse . PubMed: 28503098
  • Mildenberger J  et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2. Autophagy 13:1664-1678 (2017). PubMed: 28820283
  • Jin H  et al. Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1. Cell Stress Chaperones 22:77-85 (2017). PubMed: 27796797
  • Wu CL  et al. Roles of p62 in BDNF-dependent autophagy suppression and neuroprotection against mitochondrial dysfunction in rat cortical neurons. J Neurochem 140:845-861 (2017). PubMed: 28027414
  • Wang Q  et al. Otoprotective effects of mouse nerve growth factor in DBA/2J mice with early-onset progressive hearing loss. J Neurosci Res 95:1937-1950 (2017). PubMed: 28345280
  • Bertholet AM  et al. Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling. Cell Metab 25:811-822.e4 (2017). PubMed: 28380374
  • Jacobs RA  et al. Twenty-eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66 (2016). PubMed: 26339730
  • Zeissler ML  et al. Delta-9-tetrahydrocannabinol protects against MPP+ toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis. Oncotarget 7:46603-46614 (2016). PubMed: 27366949
  • Diokmetzidou A  et al. Desmin and aB-crystallin interplay in the maintenance of mitochondrial homeostasis and cardiomyocyte survival. J Cell Sci 129:3705-3720 (2016). PubMed: 27566162
  • Chang HC  et al. Reduction in mitochondrial iron alleviates cardiac damage during injury. EMBO Mol Med 8:247-67 (2016). IHC . PubMed: 26896449
  • D'Andrea A  et al. The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas. Oncotarget 7:72415-72430 (2016). WB . PubMed: 27635472
  • Zhang X  et al. PGC-1a/ERRa-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase ß. Antioxid Redox Signal 24:312-28 (2016). PubMed: 26421366
  • Chen G  et al. Metformin inhibits gastric cancer via the inhibition of HIF1a/PKM2 signaling. Am J Cancer Res 5:1423-34 (2015). PubMed: 26101707
  • Awuh JA  et al. Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages. Proc Natl Acad Sci U S A 112:E4272-80 (2015). PubMed: 26195781
  • Wu HM  et al. Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells. Sci Rep 5:12291 (2015). WB ; Human . PubMed: 26201611
  • Lee S  et al. High Inorganic Phosphate Intake Promotes Tumorigenesis at Early Stages in a Mouse Model of Lung Cancer. PLoS One 10:e0135582 (2015). WB ; Mouse . PubMed: 26285136
  • Johansson I  et al. The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy 11:1636-51 (2015). Human . PubMed: 26237736
  • Kim SE  et al. Upregulation of cytochrome c oxidase subunit 6b1 (Cox6b1) and formation of mitochondrial supercomplexes: implication of Cox6b1 in the effect of calorie restriction. Age (Dordr) 37:9787 (2015). PubMed: 25929654
  • Guo X  et al. Subcellular Localization of Class I Histone Deacetylases in the Developing Xenopus tectum. Front Cell Neurosci 9:510 (2015). IHC . PubMed: 26793062
  • Shi R  et al. BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke. CNS Neurosci Ther N/A:N/A (2014). Mouse . PubMed: 25230377
  • Sun R  et al. Zidovudine induces downregulation of mitochondrial deoxynucleoside kinases: implications for mitochondrial toxicity of antiviral nucleoside analogs. Antimicrob Agents Chemother 58:6758-66 (2014). Human . PubMed: 25182642
  • Estévez S  et al. Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen-activated protein kinase pathway. PLoS One 9:e112536 (2014). WB ; Human . PubMed: 25390937
  • Sargeant TJ  et al. Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization. Nat Cell Biol 16:1057-68 (2014). WB . PubMed: 25283994
  • Chen Y  et al. A nucleus-targeted alternately spliced Nix/Bnip3L protein isoform modifies nuclear factor ?B (NF?B)-mediated cardiac transcription. J Biol Chem 288:15455-65 (2013). WB ; Mouse . PubMed: 23603904
  • Traka M  et al. WDR81 is necessary for purkinje and photoreceptor cell survival. J Neurosci 33:6834-44 (2013). PubMed: 23595742
  • van der Hoeven D  et al. Fendiline inhibits K-Ras plasma membrane localization and blocks K-Ras signal transmission. Mol Cell Biol 33:237-51 (2013). PubMed: 23129805
  • Tu H  et al. Mitochondria-derived superoxide and voltage-gated sodium channels in baroreceptor neurons from chronic heart-failure rats. J Neurophysiol 107:591-602 (2012). ICC/IF ; Rat . PubMed: 22072507
  • Sun R  et al. Oxidative Stress Induced S-glutathionylation and Proteolytic Degradation of Mitochondrial Thymidine Kinase 2. J Biol Chem 287:24304-12 (2012). WB ; Human . PubMed: 22661713
  • Perrin S  et al. HIV-1 infection and first line ART induced differential responses in mitochondria from blood lymphocytes and monocytes: the ANRS EP45 "Aging" study. PLoS One 7:e41129 (2012). WB ; Human . PubMed: 22829920
  • Hanel ML  et al. Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) is a dynamic nuclear and sarcomeric protein. Differentiation 81:107-18 (2011). ICC/IF ; Human, Mouse . PubMed: 20970242
  • Tummala H  et al. The D153del Mutation in GNB3 Gene Causes Tissue Specific Signalling Patterns and an Abnormal Renal Morphology in Rge Chickens. PLoS One 6:e21156 (2011). IHC-P ; Chicken . PubMed: 21887213
  • Wong JW  et al. Is antiquitin a mitochondrial Enzyme? J Cell Biochem 109:74-81 (2010). WB, ICC/IF, Flow Cyt ; Human . PubMed: 19885858
  • Lishko PV  et al. Acid extrusion from human spermatozoa is mediated by flagellar voltage-gated proton channel. Cell 140:327-37 (2010). ICC/IF ; Human . PubMed: 20144758
  • Burnichon N  et al. SDHA is a tumor suppressor gene causing paraganglioma. Hum Mol Genet 19:3011-20 (2010). IHC-P ; Human . PubMed: 20484225
  • Das BB  et al. Role of tyrosyl-DNA phosphodiesterase (TDP1) in mitochondria. Proc Natl Acad Sci U S A 107:19790-5 (2010). WB ; Human . PubMed: 21041670
  • Taneike M  et al. Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 6:600-6 (2010). PubMed: 20431347
  • Higashi S  et al. GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation. J Neurochem 115:423-37 (2010). PubMed: 20670374

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