Key features and details
- Rabbit polyclonal to COX1 / Cyclooxygenase 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-COX1 / Cyclooxygenase 1 antibody
See all COX1 / Cyclooxygenase 1 primary antibodies
DescriptionRabbit polyclonal to COX1 / Cyclooxygenase 1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human COX1/ Cyclooxygenase 1 aa 550 to the C-terminus (C terminal) conjugated to keyhole limpet haemocyanin.
(Peptide available as
- This antibody gave a positive signal in the following human whole cell lysates: A431; HUVEC.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipoprotein metabolism
Our Abpromise guarantee covers the use of ab84602 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionMay play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
PathwayLipid metabolism; prostaglandin biosynthesis.
Sequence similaritiesBelongs to the prostaglandin G/H synthase family.
Contains 1 EGF-like domain.
Cellular localizationMicrosome membrane. Endoplasmic reticulum membrane.
- Information by UniProt
- COX 1 antibody
- COX 3 antibody
- COX-1 antibody
All lanes : Anti-COX1 / Cyclooxygenase 1 antibody (ab84602) at 1 µg/ml
Lane 1 : A431 (Human epithelial carcinoma cell line) Whole Cell Lysate
Lane 2 : HUVEC (Human Umbilical Vein Endothelial Cell) Whole Cell Lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 68 kDa
Observed band size: 71,73 kDa why is the actual band size different from the predicted?
Additional bands at: 55 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 2 minutes
This antibody was raised against an immunogen that is predicted to recognize both the short and long isofroms of Human Prostaglandin G/H synthase 1 precursor (COX1). The predicted molecular weights of the short and long isoforms are 68 kDa and 64 kDa respectively. However, COX1 contains a number of potential glycosylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted.
ab84602 has not yet been referenced specifically in any publications.