COX2 / Cyclooxygenase 2 peptide (ab213704)
Key features and details
- Purity: > 90% n/a
- Suitable for: Blocking
Description
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Product name
COX2 / Cyclooxygenase 2 peptide
See all COX2 / Cyclooxygenase 2 proteins and peptides -
Purity
> 90 % n/a. -
Animal free
No -
Nature
Synthetic -
Associated products
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Corresponding Antibody
Specifications
Our Abpromise guarantee covers the use of ab213704 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking - Blocking peptide for Anti-COX2 / Cyclooxygenase 2 antibody [EP1978Y] (ab62331)
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Form
Lyophilized -
Additional notes
This is the blocking peptide for ab62331.
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use. -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at -20°C.
General Info
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Alternative names
- COX 2
- COX-2
- COX2
see all -
Function
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. -
Pathway
Lipid metabolism; prostaglandin biosynthesis. -
Sequence similarities
Belongs to the prostaglandin G/H synthase family.
Contains 1 EGF-like domain. -
Post-translational
modificationsS-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561. -
Cellular localization
Microsome membrane. Endoplasmic reticulum membrane. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab213704 has not yet been referenced specifically in any publications.
