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  1. Link

    cox2--cyclooxygenase-2-peptide-ab213704.pdf

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Cardiovascular Blood Platelets
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COX2 / Cyclooxygenase 2 peptide (ab213704)

  • Datasheet
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Key features and details

  • Purity: > 90% n/a
  • Suitable for: Blocking

Description

  • Product name

    COX2 / Cyclooxygenase 2 peptide
    See all COX2 / Cyclooxygenase 2 proteins and peptides
  • Purity

    > 90 % n/a.

  • Animal free

    No
  • Nature

    Synthetic

    Associated products

    • Corresponding Antibody

      • Anti-COX2 / Cyclooxygenase 2 antibody [EP1978Y] (ab62331)

    Specifications

    Our Abpromise guarantee covers the use of ab213704 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Blocking - Blocking peptide for Anti-COX2 / Cyclooxygenase 2 antibody [EP1978Y] (ab62331)

    • Form

      Lyophilized
    • Additional notes

      This is the blocking peptide for ab62331.

      - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
      - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
      - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
      - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
      - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C.

    General Info

    • Alternative names

      • COX 2
      • COX-2
      • COX2
      • Cyclooxygenase
      • Cyclooxygenase 2
      • Cyclooxygenase 2b
      • Cyclooxygenase-2
      • Cyclooxygenase2
      • EC 1.14.99.1
      • fj02a10
      • Glucocorticoid-regulated inflammatory cyclooxygenase
      • Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase
      • GRIPGHS
      • hCox 2
      • Macrophage activation-associated marker protein P71/73
      • OTTHUMP00000033524
      • PES-2
      • PGG/HS
      • PGH synthase 2
      • PGH2_HUMAN
      • PGHS 2
      • PGHS-2
      • PGHS2
      • PHS 2
      • PHS II
      • PHS2
      • Prostaglandin endoperoxide synthase 2
      • Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
      • Prostaglandin G/H synthase
      • Prostaglandin G/H synthase 2
      • Prostaglandin G/H synthase 2 precursor
      • Prostaglandin G/H synthase and cyclooxygenase
      • Prostaglandin H2 synthase 2
      • Prostaglandin-endoperoxide synthase 2
      • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
      • PTGS2
      • ptgs2a
      • TIS10
      • TIS10 protein
      • unp1239
      • wu:fj02a10
      see all
    • Function

      Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
    • Pathway

      Lipid metabolism; prostaglandin biosynthesis.
    • Sequence similarities

      Belongs to the prostaglandin G/H synthase family.
      Contains 1 EGF-like domain.
    • Post-translational
      modifications

      S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.
    • Cellular localization

      Microsome membrane. Endoplasmic reticulum membrane.
    • Target information above from: UniProt accession P35354 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab213704? Please let us know so that we can cite the reference in this datasheet.

    ab213704 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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