Key features and details
- Potent, selective, non-peptide CRF1 receptor antagonist
- CAS Number: 257639-98-8
- Purity: > 99%
- Soluble in ethanol to 50 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameCP 154526 hydrochloride, non-peptide CRF1 receptor antagonist
DescriptionPotent, selective, non-peptide CRF1 receptor antagonist
Potent, selective, non-peptide corticotropin factor receptor-1 antagonist (Ki = 10 nM). Blood-brain barrier permeable. Neuroprotective and antistress agent. Active in vivo and in vitro.
Chemical nameN-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 50 mM and in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141429 has not yet been referenced specifically in any publications.