Key features and details
- p53 stabilizing agent
- CAS Number: 259199-65-0
- Purity: > 98%
- Soluble in water to 50 mM and in DMSO to 10 mM
- Form / State: Solid
- Source: Synthetic
Product nameCP-31398 dihydrochloride, p53 stabilizing agent
Descriptionp53 stabilizing agent
- Antigen NY-CO-13
- Cellular tumor antigen p53
Biological descriptionp53 stabilizing agent. Promotes active conformation of p53 and restores wild-type conformation of mutant p53 in vitro. Able to induce cell cycle arrest and apoptosis. Chemopreventative activity in vivo. Orally active.
Chemical nameN-[2-[(E)-2-(4-methoxyphenyl)ethenyl]quinazolin-4-yl]-N',N'-dimethylpropane-1,3-diamine dihydrochloride
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 50 mM and in DMSO to 10 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141643 has not yet been referenced specifically in any publications.