Anti-CPLX1 antibody (ab231347)
Key features and details
- Rabbit polyclonal to CPLX1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-CPLX1 antibody
See all CPLX1 primary antibodies -
Description
Rabbit polyclonal to CPLX1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human
Predicted to work with: Cow, Cynomolgus monkey -
Immunogen
Recombinant full length protein (His-T7-tag) corresponding to Human CPLX1 aa 1 to the C-terminus. (Expressed in E.coli)
Database link: O14810 -
Positive control
- IHC-P: Human brain tissue. WB: Recombinant human CPLX1 protein. Mouse and rat cerebrum lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab231347 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab231347 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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WB |
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 15 kDa.
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Notes |
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IHC-P
Use a concentration of 5 - 20 µg/ml. |
WB
Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 15 kDa. |
Target
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Function
Positively regulates a late step in synaptic vesicle exocytosis. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. -
Tissue specificity
Nervous system. In hippocampus and cerebellum, expressed mainly by inhibitory neurons. Overexpressed in substantia nigra from patients with Parkinson disease. -
Sequence similarities
Belongs to the complexin/synaphin family. -
Cellular localization
Cytoplasm > cytosol. Enriched at synaptic-releasing sites in mature neurons. - Information by UniProt
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Database links
- Entrez Gene: 768228 Cow
- Entrez Gene: 102114990 Cynomolgus monkey
- Entrez Gene: 10815 Human
- Entrez Gene: 12889 Mouse
- Entrez Gene: 64832 Rat
- Omim: 605032 Human
- SwissProt: Q0IIL7 Cow
- SwissProt: Q4R4N1 Cynomolgus monkey
see all -
Alternative names
- 921-S antibody
- complexin 1 antibody
- Complexin I antibody
see all
Images
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Anti-CPLX1 antibody (ab231347) at 2 µg/ml + Mouse cerebrum lysate.
Predicted band size: 15 kDa -
Anti-CPLX1 antibody (ab231347) at 2 µg/ml + Rat cerebrum lysate.
Predicted band size: 15 kDa -
Anti-CPLX1 antibody (ab231347) at 2 µg/ml + Recombinant human CPLX1 protein.
Predicted band size: 15 kDa -
Formalin-fixed, paraffin-embedded human brain tissue stained for CPLX1 using ab231347 at 20µg/ml in immunohistochemical analysis, DAB staining.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab231347 has not yet been referenced specifically in any publications.