Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab128362 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 13 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
FunctionInvolved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions.
Tissue specificityPreferentially expressed in epithelial tissues. Expressed at high levels in lung, kidney, retina, colon and mammary glands. Expressed at moderate levels in liver, spleen, pancreas, placenta and prostate.
DomainThe PDZ-binding motif is involved in the interactions with PARD6A and MPP5.
Cellular localizationApical cell membrane. Cell junction > tight junction. Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells.
- Information by UniProt
- CRB3 antibody
- CRUM3_HUMAN antibody
- crumbs homolog 3 (Drosophila) antibody
ab128362 has not yet been referenced specifically in any publications.