Recombinant
RabMAb

Recombinant Anti-CREB (phospho S133) antibody [E113] (ab32096)

Rabbit recombinant monoclonal CREB (phospho S133) antibody [E113]. Validated in WB, IP, IHC, Flow Cyt, Dot, ICC/IF and tested in Mouse, Rat, Human. Cited in 53 publication(s).

Publishing research using ab32096? Please let us know so that we can cite the reference in this datasheet.

ab32096 has been referenced in 75 publications.

  • Zhang F  et al. Effect of different charges of modified electroconvulsive seizure on the cognitive behavior in stressed rats: Effects of GluR1 phosphorylation and CaMKIIa activity. Exp Ther Med 17:748-758 (2019). PubMed: 30651859
  • Xue B  et al. Astragaloside IV Protects Primary Cerebral Cortical Neurons from Oxygen and Glucose Deprivation/Reoxygenation by Activating the PKA/CREB Pathway. Neuroscience 404:326-337 (2019). PubMed: 30708047
  • Chang PM  et al. Fucoidan?Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3ß/CREB Pathways and Metabolic Pathways in Senescent Mice. Mar Drugs 17:N/A (2019). PubMed: 30669571
  • Chen H  et al. Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis. Nat Commun 10:181 (2019). PubMed: 30643142
  • Zhang G  et al. Neuroprotective Effect of Astragalus Polysacharin on Streptozotocin (STZ)-Induced Diabetic Rats. Med Sci Monit 25:135-141 (2019). PubMed: 30610831
  • Sun C  et al. Astrocytic miR-324-5p is essential for synaptic formation by suppressing the secretion of CCL5 from astrocytes. Cell Death Dis 10:141 (2019). PubMed: 30760705
  • Hamidkhaniha S  et al. Effect of pretreatment with intracerebroventricular injection of minocycline on morphine-induced memory impairment in passive avoidance test: Role of P-CREB and c-Fos expression in the dorsal hippocampus and basolateral amygdala regions. Clin Exp Pharmacol Physiol N/A:N/A (2019). PubMed: 30919988
  • Li B  et al. Isobavachalcone exerts anti-proliferative and pro-apoptotic effects on human liver cancer cells by targeting the ERKs/RSK2 signaling pathway. Oncol Rep 41:3355-3366 (2019). PubMed: 30942462
  • Tang C  et al. MEG3 is associated with gsp oncogene regulation of growth hormone hypersecretion, proliferation and invasiveness of human GH-secreting adenomas. Oncol Lett 17:3495-3502 (2019). PubMed: 30867789
  • Tang Q  et al. Aqueous extract from You-Gui-Yin ameliorates cognitive impairment of chronic renal failure mice through targeting hippocampal CaMKIIa/CREB/BDNF and EPO/EPOR pathways. J Ethnopharmacol 239:111925 (2019). PubMed: 31055001
  • Sabbir MG & Fernyhough P Muscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neurons. Neuropharmacology 143:268-281 (2018). PubMed: 30248305
  • Kwon SJ  et al. Synergistic effect of rice bran extract and extremely low-frequency electromagnetic fields on dermal papilla/melanocytes in melanogenesis. Bioelectromagnetics 39:595-603 (2018). PubMed: 30371954
  • Ye L  et al. NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts. Bone Res 6:32 (2018). PubMed: 30455992
  • Liao YP  et al. CREB/Wnt10b mediates the effect of COX-2 on promoting BMP9-induced osteogenic differentiation via reducing adipogenic differentiation in mesenchymal stem cells. J Cell Biochem N/A:N/A (2018). PubMed: 30525243
  • Gu X  et al. Sprouty1 regulates neuritogenesis and survival of cortical neurons. J Cell Physiol N/A:N/A (2018). PubMed: 30569452
  • Snow WM  et al. Chronic dietary creatine enhances hippocampal-dependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-?B. Learn Mem 25:54-66 (2018). PubMed: 29339557
  • Pan P  et al. Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors. Int J Cancer 143:886-896 (2018). PubMed: 29524208
  • Li KL & Lin YC PM2.5 induced cardiac hypertrophy via CREB/GSK3b/SOS1 pathway and metabolomics alterations. Oncotarget 9:30748-30760 (2018). PubMed: 30112104
  • Tao X  et al. In vitro examination of microglia-neuron crosstalk with BV2 cells, and primary cultures of glia and hypothalamic neurons. Heliyon 4:e00730 (2018). PubMed: 30148218
  • Zhao W  et al. Er-Miao-Fang Extracts Inhibits Adipose Lipolysis and Reduces Hepatic Gluconeogenesis via Suppression of Inflammation. Front Physiol 9:1041 (2018). PubMed: 30154727
  • Popov DV  et al. Effect of aerobic training on baseline expression of signaling and respiratory proteins in human skeletal muscle. Physiol Rep 6:e13868 (2018). PubMed: 30198217
  • Gorbacheva AM  et al. The Risk G Allele of the Single-Nucleotide Polymorphism rs928413 Creates a CREB1-Binding Site That Activates IL33 Promoter in Lung Epithelial Cells. Int J Mol Sci 19:N/A (2018). PubMed: 30257479
  • Wei S  et al. Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes. BMC Neurosci 19:61 (2018). PubMed: 30326843
  • Suber TL  et al. FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells. Respir Res 19:206 (2018). PubMed: 30359271
  • Chowdhury PS  et al. PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8+ T Cells and Facilitates Anti-PD-1 Therapy. Cancer Immunol Res 6:1375-1387 (2018). PubMed: 30143538
  • You M  et al. Royal Jelly Alleviates Cognitive Deficits and ß-Amyloid Accumulation in APP/PS1 Mouse Model Via Activation of the cAMP/PKA/CREB/BDNF Pathway and Inhibition of Neuronal Apoptosis. Front Aging Neurosci 10:428 (2018). PubMed: 30687079
  • Wu XP  et al. MicroRNA-365 alleviates morphine analgesic tolerance via the inactivation of the ERK/CREB signaling pathway by negatively targeting ß-arrestin2. J Biomed Sci 25:10 (2018). WB . PubMed: 29415719
  • Wang R  et al. Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice. Cell Death Dis 9:352 (2018). PubMed: 29500411
  • Zhou J  et al. The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction : Mechanism for the effects of propofol on cognitive function. BMC Anesthesiol 18:35 (2018). PubMed: 29621970
  • Ruvolo PP  et al. Role of MSC-derived galectin 3 in the AML microenvironment. Biochim Biophys Acta 1865:959-969 (2018). PubMed: 29655803
  • Huang X  et al. Effects of electroacupuncture on luteal regression and steroidogenesis in ovarian hyperstimulation syndrome model rat. Life Sci 197:1-9 (2018). WB . PubMed: 29482802
  • Li C  et al. Effects of rhynchophylline on the hippocampal miRNA expression profile in ketamine-addicted rats. Prog Neuropsychopharmacol Biol Psychiatry 86:379-389 (2018). WB ; Rat . PubMed: 29476799
  • Wang Z  et al. Curcumin restrains hepatic glucose production by blocking cAMP/PKA signaling and reducing acetyl CoA accumulation in high-fat diet (HFD)-fed mice. Mol Cell Endocrinol 474:127-136 (2018). WB ; Mouse . PubMed: 29499209
  • Huang CL  et al. Gastrodia elata alleviates mutant huntingtin aggregation through mitochondrial function and biogenesis mediation. Phytomedicine 39:75-84 (2018). PubMed: 29433686
  • Meidan E  et al. High Fat Diets Composed of Palm Stearin and Olive Oil Equally Exacerbate Liver Inflammatory Damage and Metabolic Stress in Mice. Mol Nutr Food Res 62:e1700915 (2018). PubMed: 29733507
  • Gökyildirim MY  et al. Targeting CREB-binding protein overrides LPS induced radioresistance in non-small cell lung cancer cell lines. Oncotarget 9:28976-28988 (2018). PubMed: 29989005
  • Lv C  et al. Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice. Front Aging Neurosci 10:200 (2018). PubMed: 30026693
  • Wang L  et al. Oxidized phospholipids are ligands for LRP6. Bone Res 6:22 (2018). PubMed: 30038821
  • Li Y  et al. The Protective Role of Brain CYP2J in Parkinson's Disease Models. Oxid Med Cell Longev 2018:2917981 (2018). PubMed: 30046373
  • Sarowar T  et al. Object Phobia and Altered RhoA Signaling in Amygdala of Mice Lacking RICH2. Front Mol Neurosci 10:180 (2017). WB ; Mouse . PubMed: 28642683
  • Liu Y  et al. Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis. Respir Res 18:38 (2017). WB, IHC-P ; Rat . PubMed: 28222740
  • Popov DV  et al. AMPK does not play a requisite role in regulation of PPARGC1A gene expression via the alternative promoter in endurance-trained human skeletal muscle. Exp Physiol 102:366-375 (2017). PubMed: 28074493
  • Tang F  et al. CT45A1 siRNA silencing suppresses the proliferation, metastasis and invasion of lung cancer cells by downregulating the ERK/CREB signaling pathway. Mol Med Rep 16:6708-6714 (2017). PubMed: 28901509
  • Tang Y  et al. Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age. PLoS One 12:e0182471 (2017). PubMed: 28787017
  • Wang Q  et al. Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice. Osteoarthritis Cartilage 25:1868-1879 (2017). IHC ; Mouse . PubMed: 28716756
  • Popov DV  et al. Regulation ofPPARGC1Agene expression in trained and untrained human skeletal muscle. Physiol Rep 5:N/A (2017). PubMed: 29233908
  • Koschinski A & Zaccolo M Activation of PKA in cell requires higher concentration of cAMP than in vitro: implications for compartmentalization of cAMP signalling. Sci Rep 7:14090 (2017). PubMed: 29074866
  • Orts-Del'Immagine A  et al. Postnatal maturation of mouse medullo-spinal cerebrospinal fluid-contacting neurons. Neuroscience 343:39-54 (2017). PubMed: 27939302
  • Gong S  et al. Roflumilast restores cAMP/PKA/CREB signaling axis for FtMt-mediated tumor inhibition of ovarian cancer. Oncotarget 8:112341-112353 (2017). PubMed: 29348829
  • Wei Y  et al. Dexmedetomidine pretreatment attenuates propofol-induced neurotoxicity in neuronal cultures from the rat hippocampus. Mol Med Rep 14:3413-20 (2016). PubMed: 27571870
  • Zhang Y  et al. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nat Med 22:1160-1169 (2016). PubMed: 27571347
  • Pan B  et al. Chronic administration of aripiprazole activates GSK3ß-dependent signalling pathways, and up-regulates GABAA receptor expression and CREB1 activity in rats. Sci Rep 6:30040 (2016). WB ; Rat . PubMed: 27435909
  • Zhou D  et al. DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aß-induced neuronal damage via the Akt/JNK signaling pathway. Acta Pharmacol Sin 37:1401-1412 (2016). PubMed: 27498773
  • Ferenczi EA  et al. Optogenetic approaches addressing extracellular modulation of neural excitability. Sci Rep 6:23947 (2016). PubMed: 27045897
  • Terrando N  et al. Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats. Front Immunol 7:441 (2016). PubMed: 27822212
  • Liang Y  et al. CREB-regulated transcription coactivator 1 enhances CREB-dependent gene expression in spinal cord to maintain the bone cancer pain in mice. Mol Pain 12:N/A (2016). WB . PubMed: 27060162
  • He GQ  et al. Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells. Mol Brain 8:88 (2015). PubMed: 26698301
  • Ke B  et al. Inactivation of NF-?B p65 (RelA) in Liver Improves Insulin Sensitivity and Inhibits cAMP/PKA Pathway. Diabetes 64:3355-62 (2015). PubMed: 26038580
  • Snow WM  et al. Morris Water Maze Training in Mice Elevates Hippocampal Levels of Transcription Factors Nuclear Factor (Erythroid-derived 2)-like 2 and Nuclear Factor Kappa B p65. Front Mol Neurosci 8:70 (2015). WB ; Mouse . PubMed: 26635523
  • Liu F  et al. The oncoprotein HBXIP enhances angiogenesis and growth of breast cancer through modulating FGF8 and VEGF. Carcinogenesis 35:1144-53 (2014). PubMed: 24464787
  • Liu L  et al. Genetic deletion of calcium/calmodulin-dependent protein kinase kinase ß (CaMKK ß) or CaMK IV exacerbates stroke outcomes in ovariectomized (OVXed) female mice. BMC Neurosci 15:118 (2014). WB ; Mouse . PubMed: 25331941
  • Bifsha P  et al. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. PLoS Genet 10:e1004863 (2014). PubMed: 25501001
  • Yu L  et al. Cyclic adenosine monophosphate-responsive element-binding protein activation predicts an unfavorable prognosis in patients with hepatocellular carcinoma. Onco Targets Ther 7:873-9 (2014). WB, IHC . PubMed: 24926200
  • Oerlecke I  et al. Cyclic AMP enhances TGFß responses of breast cancer cells by upregulating TGFß receptor I expression. PLoS One 8:e54261 (2013). WB ; Human . PubMed: 23349840
  • Ajj H  et al. An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism. PLoS One 8:e61758 (2013). WB ; Mouse . PubMed: 23626723
  • Geng D  et al. Protective effects of EphB2 on Aß1-42 oligomer-induced neurotoxicity and synaptic NMDA receptor signaling in hippocampal neurons. Neurochem Int 63:283-90 (2013). PubMed: 23831214
  • Li X  et al. Dibutyl phthalate-induced neurotoxicity in the brain of immature and mature rat offspring. Brain Dev N/A:N/A (2013). PubMed: 24075507
  • Shorning BY  et al. Intestinal renin-angiotensin system is stimulated after deletion of Lkb1. Gut 61:202-13 (2012). Mouse . PubMed: 21813469
  • Hsieh TH  et al. Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway. FASEB J 26:778-87 (2012). WB ; Human . PubMed: 22049059
  • Mutel E  et al. Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon. Diabetes 60:3121-31 (2011). ChIP . PubMed: 22013018
  • Chandrasekar V & Dreyer JL Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference. Neuropsychopharmacology 36:1149-64 (2011). WB . PubMed: 21307844
  • Bedadala GR  et al. Lytic HSV-1 infection induces the multifunctional transcription factor Early Growth Response-1 (EGR-1) in rabbit corneal cells. Virol J 8:262 (2011). WB, ChIP . PubMed: 21619646
  • Pasquinelli V  et al. IFN-gamma production during active tuberculosis is regulated by mechanisms that involve IL-17, SLAM, and CREB. J Infect Dis 199:661-5 (2009). WB ; Human . PubMed: 19199539
  • Petrzilka S  et al. Clock Gene Modulation by TNF-{alpha} Depends on Calcium and p38 MAP Kinase Signaling. J Biol Rhythms 24:283-94 (2009). PubMed: 19625730
  • Svensson M  et al. Heat stabilization of the tissue proteome: a new technology for improved proteomics. J Proteome Res 8:974-81 (2009). PubMed: 19159280

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