Recombinant Anti-CREB (phospho S133) antibody [E113] (ab32096)

Rabbit recombinant monoclonal CREB (phospho S133) antibody [E113]. Validated in WB, IP, IHC, Flow Cyt, Dot, ICC/IF and tested in Mouse, Rat, Human. Cited in 53 publication(s).

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ab32096 has been referenced in 75 publications.

  • Zhang F  et al. Effect of different charges of modified electroconvulsive seizure on the cognitive behavior in stressed rats: Effects of GluR1 phosphorylation and CaMKIIa activity. Exp Ther Med 17:748-758 (2019). PubMed: 30651859
  • Xue B  et al. Astragaloside IV Protects Primary Cerebral Cortical Neurons from Oxygen and Glucose Deprivation/Reoxygenation by Activating the PKA/CREB Pathway. Neuroscience 404:326-337 (2019). PubMed: 30708047
  • Chang PM  et al. Fucoidan?Fucoxanthin Ameliorated Cardiac Function via IRS1/GRB2/ SOS1, GSK3ß/CREB Pathways and Metabolic Pathways in Senescent Mice. Mar Drugs 17:N/A (2019). PubMed: 30669571
  • Chen H  et al. Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis. Nat Commun 10:181 (2019). PubMed: 30643142
  • Zhang G  et al. Neuroprotective Effect of Astragalus Polysacharin on Streptozotocin (STZ)-Induced Diabetic Rats. Med Sci Monit 25:135-141 (2019). PubMed: 30610831
  • Sun C  et al. Astrocytic miR-324-5p is essential for synaptic formation by suppressing the secretion of CCL5 from astrocytes. Cell Death Dis 10:141 (2019). PubMed: 30760705
  • Hamidkhaniha S  et al. Effect of pretreatment with intracerebroventricular injection of minocycline on morphine-induced memory impairment in passive avoidance test: Role of P-CREB and c-Fos expression in the dorsal hippocampus and basolateral amygdala regions. Clin Exp Pharmacol Physiol N/A:N/A (2019). PubMed: 30919988
  • Li B  et al. Isobavachalcone exerts anti-proliferative and pro-apoptotic effects on human liver cancer cells by targeting the ERKs/RSK2 signaling pathway. Oncol Rep 41:3355-3366 (2019). PubMed: 30942462
  • Tang C  et al. MEG3 is associated with gsp oncogene regulation of growth hormone hypersecretion, proliferation and invasiveness of human GH-secreting adenomas. Oncol Lett 17:3495-3502 (2019). PubMed: 30867789
  • Tang Q  et al. Aqueous extract from You-Gui-Yin ameliorates cognitive impairment of chronic renal failure mice through targeting hippocampal CaMKIIa/CREB/BDNF and EPO/EPOR pathways. J Ethnopharmacol 239:111925 (2019). PubMed: 31055001
  • Sabbir MG & Fernyhough P Muscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neurons. Neuropharmacology 143:268-281 (2018). PubMed: 30248305
  • Kwon SJ  et al. Synergistic effect of rice bran extract and extremely low-frequency electromagnetic fields on dermal papilla/melanocytes in melanogenesis. Bioelectromagnetics 39:595-603 (2018). PubMed: 30371954
  • Ye L  et al. NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts. Bone Res 6:32 (2018). PubMed: 30455992
  • Liao YP  et al. CREB/Wnt10b mediates the effect of COX-2 on promoting BMP9-induced osteogenic differentiation via reducing adipogenic differentiation in mesenchymal stem cells. J Cell Biochem N/A:N/A (2018). PubMed: 30525243
  • Gu X  et al. Sprouty1 regulates neuritogenesis and survival of cortical neurons. J Cell Physiol N/A:N/A (2018). PubMed: 30569452
  • Snow WM  et al. Chronic dietary creatine enhances hippocampal-dependent spatial memory, bioenergetics, and levels of plasticity-related proteins associated with NF-?B. Learn Mem 25:54-66 (2018). PubMed: 29339557
  • Pan P  et al. Loss of FFAR2 promotes colon cancer by epigenetic dysregulation of inflammation suppressors. Int J Cancer 143:886-896 (2018). PubMed: 29524208
  • Li KL & Lin YC PM2.5 induced cardiac hypertrophy via CREB/GSK3b/SOS1 pathway and metabolomics alterations. Oncotarget 9:30748-30760 (2018). PubMed: 30112104
  • Tao X  et al. In vitro examination of microglia-neuron crosstalk with BV2 cells, and primary cultures of glia and hypothalamic neurons. Heliyon 4:e00730 (2018). PubMed: 30148218
  • Zhao W  et al. Er-Miao-Fang Extracts Inhibits Adipose Lipolysis and Reduces Hepatic Gluconeogenesis via Suppression of Inflammation. Front Physiol 9:1041 (2018). PubMed: 30154727
  • Popov DV  et al. Effect of aerobic training on baseline expression of signaling and respiratory proteins in human skeletal muscle. Physiol Rep 6:e13868 (2018). PubMed: 30198217
  • Gorbacheva AM  et al. The Risk G Allele of the Single-Nucleotide Polymorphism rs928413 Creates a CREB1-Binding Site That Activates IL33 Promoter in Lung Epithelial Cells. Int J Mol Sci 19:N/A (2018). PubMed: 30257479
  • Wei S  et al. Social defeat stress before pregnancy induces depressive-like behaviours and cognitive deficits in adult male offspring: correlation with neurobiological changes. BMC Neurosci 19:61 (2018). PubMed: 30326843
  • Suber TL  et al. FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells. Respir Res 19:206 (2018). PubMed: 30359271
  • Chowdhury PS  et al. PPAR-Induced Fatty Acid Oxidation in T Cells Increases the Number of Tumor-Reactive CD8+ T Cells and Facilitates Anti-PD-1 Therapy. Cancer Immunol Res 6:1375-1387 (2018). PubMed: 30143538
  • You M  et al. Royal Jelly Alleviates Cognitive Deficits and ß-Amyloid Accumulation in APP/PS1 Mouse Model Via Activation of the cAMP/PKA/CREB/BDNF Pathway and Inhibition of Neuronal Apoptosis. Front Aging Neurosci 10:428 (2018). PubMed: 30687079
  • Wu XP  et al. MicroRNA-365 alleviates morphine analgesic tolerance via the inactivation of the ERK/CREB signaling pathway by negatively targeting ß-arrestin2. J Biomed Sci 25:10 (2018). WB . PubMed: 29415719
  • Wang R  et al. Astrocytic JWA deletion exacerbates dopaminergic neurodegeneration by decreasing glutamate transporters in mice. Cell Death Dis 9:352 (2018). PubMed: 29500411
  • Zhou J  et al. The interplay of BDNF-TrkB with NMDA receptor in propofol-induced cognition dysfunction : Mechanism for the effects of propofol on cognitive function. BMC Anesthesiol 18:35 (2018). PubMed: 29621970
  • Ruvolo PP  et al. Role of MSC-derived galectin 3 in the AML microenvironment. Biochim Biophys Acta 1865:959-969 (2018). PubMed: 29655803
  • Huang X  et al. Effects of electroacupuncture on luteal regression and steroidogenesis in ovarian hyperstimulation syndrome model rat. Life Sci 197:1-9 (2018). WB . PubMed: 29482802
  • Li C  et al. Effects of rhynchophylline on the hippocampal miRNA expression profile in ketamine-addicted rats. Prog Neuropsychopharmacol Biol Psychiatry 86:379-389 (2018). WB ; Rat . PubMed: 29476799
  • Wang Z  et al. Curcumin restrains hepatic glucose production by blocking cAMP/PKA signaling and reducing acetyl CoA accumulation in high-fat diet (HFD)-fed mice. Mol Cell Endocrinol 474:127-136 (2018). WB ; Mouse . PubMed: 29499209
  • Huang CL  et al. Gastrodia elata alleviates mutant huntingtin aggregation through mitochondrial function and biogenesis mediation. Phytomedicine 39:75-84 (2018). PubMed: 29433686
  • Meidan E  et al. High Fat Diets Composed of Palm Stearin and Olive Oil Equally Exacerbate Liver Inflammatory Damage and Metabolic Stress in Mice. Mol Nutr Food Res 62:e1700915 (2018). PubMed: 29733507
  • Gökyildirim MY  et al. Targeting CREB-binding protein overrides LPS induced radioresistance in non-small cell lung cancer cell lines. Oncotarget 9:28976-28988 (2018). PubMed: 29989005
  • Lv C  et al. Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice. Front Aging Neurosci 10:200 (2018). PubMed: 30026693
  • Wang L  et al. Oxidized phospholipids are ligands for LRP6. Bone Res 6:22 (2018). PubMed: 30038821
  • Li Y  et al. The Protective Role of Brain CYP2J in Parkinson's Disease Models. Oxid Med Cell Longev 2018:2917981 (2018). PubMed: 30046373
  • Sarowar T  et al. Object Phobia and Altered RhoA Signaling in Amygdala of Mice Lacking RICH2. Front Mol Neurosci 10:180 (2017). WB ; Mouse . PubMed: 28642683
  • Liu Y  et al. Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis. Respir Res 18:38 (2017). WB, IHC-P ; Rat . PubMed: 28222740
  • Popov DV  et al. AMPK does not play a requisite role in regulation of PPARGC1A gene expression via the alternative promoter in endurance-trained human skeletal muscle. Exp Physiol 102:366-375 (2017). PubMed: 28074493
  • Tang F  et al. CT45A1 siRNA silencing suppresses the proliferation, metastasis and invasion of lung cancer cells by downregulating the ERK/CREB signaling pathway. Mol Med Rep 16:6708-6714 (2017). PubMed: 28901509
  • Tang Y  et al. Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age. PLoS One 12:e0182471 (2017). PubMed: 28787017
  • Wang Q  et al. Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice. Osteoarthritis Cartilage 25:1868-1879 (2017). IHC ; Mouse . PubMed: 28716756
  • Popov DV  et al. Regulation ofPPARGC1Agene expression in trained and untrained human skeletal muscle. Physiol Rep 5:N/A (2017). PubMed: 29233908
  • Koschinski A & Zaccolo M Activation of PKA in cell requires higher concentration of cAMP than in vitro: implications for compartmentalization of cAMP signalling. Sci Rep 7:14090 (2017). PubMed: 29074866
  • Orts-Del'Immagine A  et al. Postnatal maturation of mouse medullo-spinal cerebrospinal fluid-contacting neurons. Neuroscience 343:39-54 (2017). PubMed: 27939302
  • Gong S  et al. Roflumilast restores cAMP/PKA/CREB signaling axis for FtMt-mediated tumor inhibition of ovarian cancer. Oncotarget 8:112341-112353 (2017). PubMed: 29348829
  • Wei Y  et al. Dexmedetomidine pretreatment attenuates propofol-induced neurotoxicity in neuronal cultures from the rat hippocampus. Mol Med Rep 14:3413-20 (2016). PubMed: 27571870
  • Zhang Y  et al. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nat Med 22:1160-1169 (2016). PubMed: 27571347
  • Pan B  et al. Chronic administration of aripiprazole activates GSK3ß-dependent signalling pathways, and up-regulates GABAA receptor expression and CREB1 activity in rats. Sci Rep 6:30040 (2016). WB ; Rat . PubMed: 27435909
  • Zhou D  et al. DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aß-induced neuronal damage via the Akt/JNK signaling pathway. Acta Pharmacol Sin 37:1401-1412 (2016). PubMed: 27498773
  • Ferenczi EA  et al. Optogenetic approaches addressing extracellular modulation of neural excitability. Sci Rep 6:23947 (2016). PubMed: 27045897
  • Terrando N  et al. Systemic HMGB1 Neutralization Prevents Postoperative Neurocognitive Dysfunction in Aged Rats. Front Immunol 7:441 (2016). PubMed: 27822212
  • Liang Y  et al. CREB-regulated transcription coactivator 1 enhances CREB-dependent gene expression in spinal cord to maintain the bone cancer pain in mice. Mol Pain 12:N/A (2016). WB . PubMed: 27060162
  • He GQ  et al. Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells. Mol Brain 8:88 (2015). PubMed: 26698301
  • Ke B  et al. Inactivation of NF-?B p65 (RelA) in Liver Improves Insulin Sensitivity and Inhibits cAMP/PKA Pathway. Diabetes 64:3355-62 (2015). PubMed: 26038580
  • Snow WM  et al. Morris Water Maze Training in Mice Elevates Hippocampal Levels of Transcription Factors Nuclear Factor (Erythroid-derived 2)-like 2 and Nuclear Factor Kappa B p65. Front Mol Neurosci 8:70 (2015). WB ; Mouse . PubMed: 26635523
  • Liu F  et al. The oncoprotein HBXIP enhances angiogenesis and growth of breast cancer through modulating FGF8 and VEGF. Carcinogenesis 35:1144-53 (2014). PubMed: 24464787
  • Liu L  et al. Genetic deletion of calcium/calmodulin-dependent protein kinase kinase ß (CaMKK ß) or CaMK IV exacerbates stroke outcomes in ovariectomized (OVXed) female mice. BMC Neurosci 15:118 (2014). WB ; Mouse . PubMed: 25331941
  • Bifsha P  et al. Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra. PLoS Genet 10:e1004863 (2014). PubMed: 25501001
  • Yu L  et al. Cyclic adenosine monophosphate-responsive element-binding protein activation predicts an unfavorable prognosis in patients with hepatocellular carcinoma. Onco Targets Ther 7:873-9 (2014). WB, IHC . PubMed: 24926200
  • Oerlecke I  et al. Cyclic AMP enhances TGFß responses of breast cancer cells by upregulating TGFß receptor I expression. PLoS One 8:e54261 (2013). WB ; Human . PubMed: 23349840
  • Ajj H  et al. An alkylphenol mix promotes seminoma derived cell proliferation through an ERalpha36-mediated mechanism. PLoS One 8:e61758 (2013). WB ; Mouse . PubMed: 23626723
  • Geng D  et al. Protective effects of EphB2 on Aß1-42 oligomer-induced neurotoxicity and synaptic NMDA receptor signaling in hippocampal neurons. Neurochem Int 63:283-90 (2013). PubMed: 23831214
  • Li X  et al. Dibutyl phthalate-induced neurotoxicity in the brain of immature and mature rat offspring. Brain Dev N/A:N/A (2013). PubMed: 24075507
  • Shorning BY  et al. Intestinal renin-angiotensin system is stimulated after deletion of Lkb1. Gut 61:202-13 (2012). Mouse . PubMed: 21813469
  • Hsieh TH  et al. Phthalates induce proliferation and invasiveness of estrogen receptor-negative breast cancer through the AhR/HDAC6/c-Myc signaling pathway. FASEB J 26:778-87 (2012). WB ; Human . PubMed: 22049059
  • Mutel E  et al. Control of blood glucose in the absence of hepatic glucose production during prolonged fasting in mice: induction of renal and intestinal gluconeogenesis by glucagon. Diabetes 60:3121-31 (2011). ChIP . PubMed: 22013018
  • Chandrasekar V & Dreyer JL Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference. Neuropsychopharmacology 36:1149-64 (2011). WB . PubMed: 21307844
  • Bedadala GR  et al. Lytic HSV-1 infection induces the multifunctional transcription factor Early Growth Response-1 (EGR-1) in rabbit corneal cells. Virol J 8:262 (2011). WB, ChIP . PubMed: 21619646
  • Pasquinelli V  et al. IFN-gamma production during active tuberculosis is regulated by mechanisms that involve IL-17, SLAM, and CREB. J Infect Dis 199:661-5 (2009). WB ; Human . PubMed: 19199539
  • Petrzilka S  et al. Clock Gene Modulation by TNF-{alpha} Depends on Calcium and p38 MAP Kinase Signaling. J Biol Rhythms 24:283-94 (2009). PubMed: 19625730
  • Svensson M  et al. Heat stabilization of the tissue proteome: a new technology for improved proteomics. J Proteome Res 8:974-81 (2009). PubMed: 19159280

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