Anti-CREBBP antibody - ChIP Grade (ab2832)

Rabbit polyclonal KAT3A / CBP antibody. Validated in WB, IP, IHC, ChIP, Inhibition, ICC/IF, CHIPseq and tested in Mouse, Rat, Human. Cited in 37 publication(s). Independently reviewed in 4 review(s).

Publishing research using ab2832? Please let us know so that we can cite the reference in this datasheet.

ab2832 has been referenced in 43 publications.

  • Dong H  et al. Activation of LncRNA TINCR by H3K27 acetylation promotes Trastuzumab resistance and epithelial-mesenchymal transition by targeting MicroRNA-125b in breast Cancer. Mol Cancer 18:3 (2019). PubMed: 30621694
  • Chen F  et al. lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/ß-catenin pathway in oral squamous cell carcinoma. Int J Oncol 54:1183-1194 (2019). PubMed: 30720068
  • Wu Y  et al. Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis. Cancer Res 78:671-684 (2018). PubMed: 29212856
  • Dong H  et al. SP1-induced lncRNA AGAP2-AS1 expression promotes chemoresistance of breast cancer by epigenetic regulation of MyD88. J Exp Clin Cancer Res 37:202 (2018). PubMed: 30157918
  • Singh S  et al. Decreased level of histone acetylation in the infralimbic prefrontal cortex following immediate extinction may result in deficit of extinction memory. Brain Res Bull 140:355-364 (2018). PubMed: 29908895
  • Gökyildirim MY  et al. Targeting CREB-binding protein overrides LPS induced radioresistance in non-small cell lung cancer cell lines. Oncotarget 9:28976-28988 (2018). PubMed: 29989005
  • Subbanna S  et al. Activity-dependent Signaling and Epigenetic Abnormalities in Mice Exposed to Postnatal Ethanol. Neuroscience N/A:N/A (2018). PubMed: 30031835
  • Liang Y  et al. LncRNA CASC9 promotes esophageal squamous cell carcinoma metastasis through upregulating LAMC2 expression by interacting with the CREB-binding protein. Cell Death Differ 25:1980-1995 (2018). PubMed: 29511340
  • Chatterjee S  et al. Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator. EMBO Mol Med 10:N/A (2018). PubMed: 30275019
  • Kosmidis S  et al. RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss. Cell Rep 25:959-973.e6 (2018). PubMed: 30355501
  • Liang Y  et al. A novel long noncoding RNA linc00460 up-regulated by CBP/P300 promotes carcinogenesis in esophageal squamous cell carcinoma. Biosci Rep 37:N/A (2017). PubMed: 28939763
  • Benoit YD  et al. Sam68 Allows Selective Targeting of Human Cancer Stem Cells. Cell Chem Biol 24:833-844.e9 (2017). PubMed: 28648376
  • Bose DA  et al. RNA Binding to CBP Stimulates Histone Acetylation and Transcription. Cell 168:135-149.e22 (2017). PubMed: 28086087
  • Mews P  et al. Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory. Nature 546:381-386 (2017). PubMed: 28562591
  • Tsukamoto D  et al. HNF-4 participates in the hibernation-associated transcriptional regulation of the chipmunk hibernation-related protein gene. Sci Rep 7:44279 (2017). ChIP . PubMed: 28281641
  • Liu Y  et al. Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis. Respir Res 18:38 (2017). WB ; Rat . PubMed: 28222740
  • Duan S  et al. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Nat Commun 6:10068 (2015). ChIP . PubMed: 26632666
  • Telese F  et al. LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation. Neuron 86:696-710 (2015). PubMed: 25892301
  • Gao Y  et al. Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer. Int J Clin Exp Pathol 7:760-7 (2014). IHC-P ; Human . PubMed: 24551300
  • Das C  et al. Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation. Proc Natl Acad Sci U S A 111:E1072-81 (2014). WB ; Human . PubMed: 24616510
  • Shen W  et al. Epigenetic modification of the leptin promoter in diet-induced obese mice and the effects of N-3 polyunsaturated Fatty acids. Sci Rep 4:5282 (2014). ChIP ; Mouse . PubMed: 24923522
  • Arensman MD  et al. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Mol Cancer Ther 13:2303-14 (2014). PubMed: 25082960
  • Park-Min KH  et al. Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation. Nat Commun 5:5418 (2014). ChIP ; Human . PubMed: 25391636
  • Li Q  et al. Hepatitis C virus infection activates an innate pathway involving IKK-a in lipogenesis and viral assembly. Nat Med 19:722-9 (2013). ChIP . PubMed: 23708292
  • Liu Y  et al. Akt kinase targets the association of CBP with histone H3 to regulate the acetylation of lysine K18. FEBS Lett 587:847-53 (2013). PubMed: 23434580
  • Huggins CJ  et al. C/EBP? suppresses senescence and inflammatory gene expression by heterodimerizing with C/EBPß. Mol Cell Biol 33:3242-58 (2013). IP ; Mouse . PubMed: 23775115
  • Tumes DJ  et al. The polycomb protein Ezh2 regulates differentiation and plasticity of CD4(+) T helper type 1 and type 2 cells. Immunity 39:819-32 (2013). PubMed: 24238339
  • Bui C  et al. cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis. FASEB J : (2012). Human . PubMed: 22505473
  • Liu Y  et al. Oncogene Ras/phosphatidylinositol 3-kinase signaling targets histone H3 acetylation at lysine 56. J Biol Chem 287:41469-80 (2012). PubMed: 22982396
  • Li Y  et al. And-1 is required for the stability of histone acetyltransferase Gcn5. Oncogene 31:643-52 (2012). IF . PubMed: 21725360
  • Blackford JA  et al. Identification of location and kinetically defined mechanism of cofactors and reporter genes in the cascade of steroid-regulated transactivation. J Biol Chem 287:40982-95 (2012). WB . PubMed: 23055525
  • Ichi S  et al. Role of Pax3 acetylation in the regulation of Hes1 and Neurog2. Mol Biol Cell 22:503-12 (2011). ChIP ; Mouse . PubMed: 21169561
  • Place AT  et al. Cooperative role of Caveolin-1 and C-terminal Src kinase binding protein in C-terminal Src kinase-mediated negative regulation of c-Src. Mol Pharmacol 80:665-72 (2011). WB ; Mouse . PubMed: 21778303
  • Ram O  et al. Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell 147:1628-39 (2011). WB, CHIPseq ; Human . PubMed: 22196736
  • Chan WI  et al. The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells. Mol Cell Biol 31:5046-60 (2011). ChIP ; Mouse . PubMed: 22006020
  • Montemayor C  et al. Genome-wide analysis of binding sites and direct target genes of the orphan nuclear receptor NR2F1/COUP-TFI. PLoS One 5:e8910 (2010). ChIP ; Mouse . PubMed: 20111703
  • Chan EC  et al. Prostacyclin receptor suppresses cardiac fibrosis: role of CREB phosphorylation. J Mol Cell Cardiol 49:176-85 (2010). WB, IP ; Mouse . PubMed: 20403362
  • Carter CL  et al. Phosphorylated p68 RNA helicase activates snail1 transcription by promoting HDAC1 dissociation from the snail1 promoter. Oncogene : (2010). ChIP ; Human . PubMed: 20676135
  • Sakurai T  et al. Function of a transcription factor CDX2 beyond its trophectoderm lineage specification. Endocrinology 151:5873-81 (2010). WB . PubMed: 20962045
  • Béguelin W  et al. Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3. Mol Cell Biol 30:5456-72 (2010). PubMed: 20876300
  • Das C  et al. CBP/p300-mediated acetylation of histone H3 on lysine 56. Nature 459:113-7 (2009). PubMed: 19270680
  • Gomez RA  et al. CBP and p300 are essential for renin cell identity and morphological integrity of the kidney. Am J Physiol Heart Circ Physiol 296:H1255-62 (2009). PubMed: 19252086
  • Doghman M  et al. Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer. Mol Endocrinol 21:2968-87 (2007). PubMed: 17761949

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