Overview

  • Product name

  • Description

    Rabbit polyclonal to CREBRF/LRF
  • Host species

    Rabbit
  • Specificity

    ab26262 recognises LOC153222.
  • Tested applications

    Suitable for: ELISA, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Dog
  • Immunogen

    Synthetic peptide within Human CREBRF/LRF aa 365-412 (internal sequence). The exact sequence is proprietary.
    Sequence:

    DDEDHDEGFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYEND


    Database link: Q8IUR6

  • Positive control

    • Fetal lung lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab26262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/12500.
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 47 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function

    Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.
  • Sequence similarities

    Belongs to the bZIP family. CREBRF subfamily.
    Contains 1 bZIP (basic-leucine zipper) domain.
  • Post-translational
    modifications

    Probably degraded by the proteasome.
  • Cellular localization

    Nucleus. Colocalizes with CREB3 in nuclear foci.
  • Information by UniProt
  • Database links

  • Alternative names

    • adult retina protein antibody
    • C5orf41 antibody
    • Chromosome 5 Open Reading Frame 41 antibody
    • CREB3 regulatory factor antibody
    • CREBRF antibody
    • CRERF_HUMAN antibody
    • Hypothetical protein antibody
    • LRF antibody
    • Luman recruitment factor antibody
    see all

Images

  • Anti-CREBRF/LRF antibody (ab26262) at 0.5 µg/ml + Fetal lung lysate

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size: 47 kDa
    Observed band size: 50 kDa
    why is the actual band size different from the predicted?

References

ab26262 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab26262.
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