Anti-CREG1/CREG antibody (ab191909)
Key features and details
- Rabbit polyclonal to CREG1/CREG
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-CREG1/CREG antibody
See all CREG1/CREG primary antibodies -
Description
Rabbit polyclonal to CREG1/CREG -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human CREG1/CREG.
Database link: O75629 -
Positive control
- HEK293T, RAW 264.7 and PC12 whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab191909 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab191909 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 24 kDa.
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Notes |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 24 kDa. |
Target
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Function
May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R. -
Sequence similarities
Belongs to the CREG family. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 8804 Human
- Entrez Gene: 433375 Mouse
- Entrez Gene: 289185 Rat
- SwissProt: O75629 Human
- SwissProt: O88668 Mouse
- Unigene: 5710 Human
- Unigene: 294885 Mouse
- Unigene: 468745 Mouse
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Alternative names
- Cellular repressor of E1A stimulated genes 1 antibody
- Cellular repressor of E1A-stimulated genes 1 antibody
- CREG antibody
see all
Images
Datasheets and documents
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Datasheet download
References (2)
ab191909 has been referenced in 2 publications.
- Yang L et al. Creg in Hepatocytes Ameliorates Liver Ischemia/Reperfusion Injury in a TAK1-Dependent Manner in Mice. Hepatology 69:294-313 (2019). PubMed: 30076625
- Liu Y et al. Up-Regulation of CREG Expression by the Transcription Factor GATA1 Inhibits High Glucose- and High Palmitate-Induced Apoptosis in Human Umbilical Vein Endothelial Cells. PLoS One 11:e0154861 (2016). PubMed: 27139506