Key features and details
- Rabbit polyclonal to CRELD1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-CRELD1 antibody
See all CRELD1 primary antibodies
DescriptionRabbit polyclonal to CRELD1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Horse, Guinea pig, Cow, Cat, Dog, Human
- Mouse lung lysate.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab140346 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa.|
Tissue specificityHighly expressed in fetal lung, liver, kidney, adult heart, brain and skeletal muscle. Weakly expressed in placenta, fetal brain, and adult lung, liver, kidney and pancreas.
Involvement in diseaseDefects in CRELD1 may be the cause of susceptibility to atrioventricular septal defect type 2 (AVSD2) [MIM:606217]. AVSD is a spectrum of cardiac malformations that result in a persistent common atrioventricular canal. The complete form of AVSD involves underdevelopment of the lower part of the atrial septum and the upper part of the ventricular septum. A less severe form, known as partial AVSD or ostium primum atrial septal defect has a deficiency of the atrial septum. Complete AVSD are clinically apparent at birth, whereas less severe forms, such as an isolated cleft mitral valve or small defects of the atrial or ventricular septa may go undetected.
Sequence similaritiesBelongs to the CRELD family.
Contains 2 EGF-like domains.
Contains 2 FU (furin-like) repeats.
- Information by UniProt
- Atrioventricular septal defect 2 antibody
- AVSD2 antibody
- CIRRIN antibody
ab140346 has been referenced in 1 publication.
- D'Alessandro M et al. CRELD1 is an evolutionarily-conserved maturational enhancer of ionotropic acetylcholine receptors. Elife 7:N/A (2018). PubMed: 30407909