Overview

  • Product name

  • Description

    Rabbit polyclonal to CRF1/CRHR1
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse, Horse, Hamster, Cow, Dog, Pig, Bird, Lizard, Monkey, Zebrafish, Gorilla, Common marmoset, Elephant
  • Immunogen

    Synthetic peptide corresponding to Human CRF1/CRHR1 (N terminal). Synthetic peptide, corresponding to 18 amino acids from the N-terminal extracellular domain of Human CRF1/CRHR1.
    Database link: P34998

  • Positive control

    • Human brain (neurons and glia) tissue; Rat hypothalamus tissue.
  • General notes

     This product was previously labelled as CRF1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab150561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 21 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    This is a receptor for corticotropin releasing factor. Shows high-affinity CRF binding. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
  • Tissue specificity

    Predominantly expressed in the cerebellum, pituitary, cerebral cortex and olfactory lobe.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family.
  • Post-translational
    modifications

    C-terminal Ser or Thr residues may be phosphorylated.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Corticotropin releasing factor type 1 receptor antibody
    • corticotropin releasing hormone receptor 1 antibody
    • Corticotropin-releasing factor receptor 1 antibody
    • Corticotropin-releasing hormone receptor 1 antibody
    • CRF R antibody
    • crf receptor 1 antibody
    • crf receptor type 1 antibody
    • crf type 1 antibody
    • CRF-R antibody
    • CRF-R-1 antibody
    • CRF-R1 antibody
    • CRF1 antibody
    • CRFR antibody
    • CRFR-1 antibody
    • CRFR1 antibody
    • CRFR1_HUMAN antibody
    • CRH-R-1 antibody
    • CRH-R1 antibody
    • CRH-R1h antibody
    • CRHR antibody
    • Crhr1 antibody
    • CRHR1f antibody
    • CRHR1L antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat hypothalamus tissue, labeling CRF1/CRHR1 using ab150561 at 21 µg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain, neurons and glia, tissue, labeling CRF1/CRHR1 using ab150561 at 21 µg/ml.

References

ab150561 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (Frozen sections)
Sample
Human Tissue sections (Normal haired facial skin)
Permeabilization
No
Specification
Normal haired facial skin
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: RT°C
Fixative
Acetone

Abcam user community

Verified customer

Submitted Feb 28 2018

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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